MicroRNA and ovarian cancer

Publication:
MicroRNA and ovarian cancer

dc.contributor.author	Corney, David C.	es
dc.contributor.author	Nikitin, Alexander Yu.	es
dc.date.accessioned	2013-01-22T10:03:15Z
dc.date.available	2013-01-22T10:03:15Z
dc.date.issued	2008
dc.description.abstract	Ovarian cancer remains a leading cause of morbidity and mortality, with little change in survival rates over the past 30 years. Research in the molecular biology underlying the disease demonstrates frequent mutation in the p53/Rb/p16 tumor suppressor pathways and activation of c-myc, K-ras and Akt oncogenic signaling. Recently, miRNAs have been demonstrated to play an important role in controlling proliferation, apoptosis and many other processes altered in the cancer state. In this review we discuss a number of recent publications that implicate a role for microRNAs in ovarian cancer and assess how this new field may improve our fundamental understanding of the disease and provide improved diagnostic and therapeutic approaches.	es
dc.format	application/pdf	es
dc.format.extent	9	es
dc.identifier.issn	0213-3911	es
dc.identifier.uri	http://hdl.handle.net/10201/29833
dc.language	eng	es
dc.publisher	Murcia : F. Hernández	es
dc.relation.ispartof	Histology and histopathology	es
dc.rights	info:eu-repo/semantics/openAccess	es
dc.subject	Carcinogenesis	es
dc.subject	Epithelial ovarian cancer	es
dc.subject.other	616.6 - Patología del sistema genitourinario	es
dc.title	MicroRNA and ovarian cancer	es
dc.type	info:eu-repo/semantics/article	es
dspace.entity.type	Publication	es

Now showing 1 - 1 of 1

Sin licencia Creative Commons.