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A meta-analysis of gut microbiota in children with autism

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dc.contributor.authorAndreo Martínez, Pedro
dc.contributor.authorRubio Aparicio, María
dc.contributor.authorSánchez Meca, Julio
dc.contributor.authorVeas, Alejandro
dc.contributor.authorMartínez González, Agustín Ernesto
dc.contributor.departmentQuímica Agrícola, Geología y Edafología
dc.date.accessioned2024-01-28T13:00:42Z
dc.date.available2024-01-28T13:00:42Z
dc.date.issued2021
dc.description©2021. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/ This document is the accepted, version of a Published Work that appeared in final form in Journal of Autism and Developmental Disorders. To access the final edited and published work see https://doi.org/10.1007/s10803-021-05002-yes
dc.description.abstractPrevious studies have reported dysbiosis in the gut microbiota (GM) of children with autism spectrum disorders (ASD), which may be a determining factor on child development through the microbiota-gut-brain axis. However, it is not clear if there is a specific group of dysbiotic bacteria in ASD. The aim of this study was to carry out a meta-analysis on the studies that analyze GM in children with ASD. 18 studies fulfilled our selection criteria. Our results showed a lower relative abundance of Streptococcus (SMD+ = − 0.999; 95% CI − 1.549, − 0.449) and Bifidobacterium genera (SMD+ = − 0.513; 95% CI − 0.953, − 0.073) in children with ASD. Overall, the Bifidobacterium genera is involved. However, differences found between studies are attributed to factors such as reporting bias.es
dc.formatapplication/pdfes
dc.format.extent14es
dc.identifier.citationJournal of Autism and Developmental Disorders, 52, 2022, 1374–1387
dc.identifier.doihttps://doi.org/10.1007/s10803-021-05002-y
dc.identifier.issn1573-3432
dc.identifier.urihttp://hdl.handle.net/10201/137879
dc.languageenges
dc.publisherSpringeres
dc.relationSin financiación externa a la Universidades
dc.relation.publisherversionhttps://link.springer.com/article/10.1007/s10803-021-05002-yes
dc.rightsAttribution-NonCommercial-NoDerivates 4.0 International
dc.rights.accessRightsinfo:eu-repo/semantics/openAccess
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/
dc.subjectAutism spectrum disorders (ASD)es
dc.subjectGut microbiotaes
dc.subjectMicrobiota-gut-brain axises
dc.subjectSystematic reviewes
dc.subjectMetaanalysises
dc.titleA meta-analysis of gut microbiota in children with autismes
dc.typeinfo:eu-repo/semantics/articlees
dspace.entity.typePublicationes
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