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Infantile cortical hyperostosis (Caffey disease): ultrastructural and immunohistochemical characterization of the peritrabecular cells

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Infantile cortical hyperostosis Caffey disease ultrastructural and immunohistochemical characterization of the peritrabecular cells.pdf(3.64 MB)
Date
1990
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Authors
Quacci, Daniela ; Pazzaglia, Ugo Ernesto ; Dell`Orbo, Carlo ; Grazzia Ennas, María
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Publisher
Murcia : F. Hernández
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DOI
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info:eu-repo/semantics/article
Description
Abstract
The ultrastructure and the immunohistochemical pattern of the cells which are responsible for the bone resorption in the cortical infantile hyperostosis were investigated. The osteoclasts present a great positivity to MB1 antigen and a low positivity to OKM5. Mononuclear cells with primary lysosomes, looking like osteoclast ones are present in high concentration in peritrabecular spaces. These cells show a high positivity to OKM5 antigen and a low positivity to MB1 antigen. The mononuclear granulated cells are positive to tartrate-resistent acid phosphatase. The possible common origin and their co-operation in bone resorption is discussed.
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Infantile cortical hyperostosis , Immunohistochemistry
Citation
URI
http://hdl.handle.net/10201/18150
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Histology and histopathology Vol. 5, nº 2 (1990)
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