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IBL-like T cell lymphoma expressing monoclonal gammopathy (macroglobulinemia) in the serum

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dc.contributor.authorKasajima, Takeshi
dc.contributor.authorMasuda, Akihiro
dc.contributor.authorMatsuda, Mikio
dc.contributor.authorImai, Yutaka
dc.contributor.authorTobinai, Kensei
dc.date.accessioned2011-01-27T12:52:36Z
dc.date.available2011-01-27T12:52:36Z
dc.date.issued1989
dc.description.abstractA case of IBL-like T cell lymphoma with serum monoclonal gammopathy was reported. A 58- year-old woman, who had suffered from heart failure. was admitted because of asthma attack, fever and lyrnphadenopathy. Leucopenia with a small amount of atypical lymphocytes was detected. Serum analysis showed monoclonal elevation of IgM-K (M-protein) and hv~erviscositv. Urinarv Bence-Jones urotein was diiected. Lymph &de biopsy rAealed the disappearance of normal structure and proliferation of T cells with pale cells which characterized IBL-like T cell lymphoma. Immunocytochemistry revealed the pale cells to bear T cell markers (MT-1, CD 5, CD 8 or CD 4) and IgM-positive cell distribution. Tonsilar biopsy showed the infiltration of atypical lymphoids and pale cells. Bone marrow biopsy showed moderate lymphoplasmacytoid proliferation with lymph follicles. Clinical data and serum analysis suggested macroglobulinemia. Additional lymph node biopsy was performed and revealed IBL-like T cell lymphoma. IBLlike T cell lymphoma is characterized by polyclonal hypergammaglobulinemia. The present case probably occurred initially as IBL-like T cell lymphoma and lymphoplasmacytoid cell proliferation might have followed due to an excess of CD 4' cellses
dc.formatapplication/pdfes
dc.format.extent9es
dc.identifier.issn0213-3911
dc.identifier.urihttp://hdl.handle.net/10201/18074
dc.languageenges
dc.publisherMurcia : F. Hernándezes
dc.rightsinfo:eu-repo/semantics/openAccesses
dc.subjectMacroglobulinemiaes
dc.subjectImmunocytochemistryes
dc.subject.otherCDU::6 - Ciencias aplicadas::61 - Medicinaes
dc.titleIBL-like T cell lymphoma expressing monoclonal gammopathy (macroglobulinemia) in the serumes
dc.typeinfo:eu-repo/semantics/articlees
dspace.entity.typePublicationes
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Histology and histopathology Vol. 4, nº 3 (1989)