Publication:
The expression of Smad signaling pathway in myocardium and potential therapeutic effects

dc.contributor.authorDuan, Yongjian
dc.contributor.authorZhu, Wei
dc.contributor.authorLiu, Min
dc.contributor.authorAshraf, Muhammad
dc.contributor.authorXu, Meifeng
dc.date.accessioned2022-02-24T07:34:08Z
dc.date.available2022-02-24T07:34:08Z
dc.date.issued2017
dc.description.abstractMyocardial infarction (MI) is a lifethreatening disease. The expression of Smad proteins in the ischemic myocardium changes significantly following myocardial infarction, suggesting a close relationship between Smad proteins and heart remodeling. Moreover, it is known that the expression of Smads is regulated by transforming growth factor-β (TGF-β) and bone morphogenetic proteins (BMP). Based on these findings, regulating the expression of Smad proteins by targeting TGF-β and BMP in the ischemic myocardium may be considered to be a possible therapeutic strategy for the treatment of myocardial infarctiones
dc.formatapplication/pdfes
dc.format.extent9es
dc.identifier.citationHistology and Histopathology, Vol.32, nº7, (2017)
dc.identifier.doiDOI:10.14670/ HH-11-845
dc.identifier.issn1699-5848
dc.identifier.issn0213-3911
dc.identifier.urihttp://hdl.handle.net/10201/117363
dc.languageenges
dc.publisherUniversidad de Murcia. Departamento de Biología Celular e Histologíaes
dc.relationSin financiación externa a la Universidades
dc.rightsinfo:eu-repo/semantics/openAccesses
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 Internacional*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subjectMyocardial infarctiones
dc.subjectSmades
dc.subjectTGF-βes
dc.subjectBMPes
dc.subject.otherCDU::6 - Ciencias aplicadas::61 - Medicina::616 - Patología. Medicina clínica. Oncologíaes
dc.titleThe expression of Smad signaling pathway in myocardium and potential therapeutic effectses
dc.typeinfo:eu-repo/semantics/articlees
dspace.entity.typePublicationes
Files
Original bundle
Now showing 1 - 1 of 1
Loading...
Thumbnail Image
Name:
Duan-32-651-659-2017.pdf
Size:
1.6 MB
Format:
Adobe Portable Document Format
Description:
License bundle
Now showing 1 - 1 of 1
Loading...
Thumbnail Image
Name:
license.txt
Size:
1.39 KB
Format:
Item-specific license agreed upon to submission
Description: