Publication: The expression of Smad signaling pathway in myocardium and potential therapeutic effects
| dc.contributor.author | Duan, Yongjian | |
| dc.contributor.author | Zhu, Wei | |
| dc.contributor.author | Liu, Min | |
| dc.contributor.author | Ashraf, Muhammad | |
| dc.contributor.author | Xu, Meifeng | |
| dc.date.accessioned | 2022-02-24T07:34:08Z | |
| dc.date.available | 2022-02-24T07:34:08Z | |
| dc.date.issued | 2017 | |
| dc.description.abstract | Myocardial infarction (MI) is a lifethreatening disease. The expression of Smad proteins in the ischemic myocardium changes significantly following myocardial infarction, suggesting a close relationship between Smad proteins and heart remodeling. Moreover, it is known that the expression of Smads is regulated by transforming growth factor-β (TGF-β) and bone morphogenetic proteins (BMP). Based on these findings, regulating the expression of Smad proteins by targeting TGF-β and BMP in the ischemic myocardium may be considered to be a possible therapeutic strategy for the treatment of myocardial infarction | es |
| dc.format | application/pdf | es |
| dc.format.extent | 9 | es |
| dc.identifier.citation | Histology and Histopathology, Vol.32, nº7, (2017) | |
| dc.identifier.doi | DOI:10.14670/ HH-11-845 | |
| dc.identifier.issn | 1699-5848 | |
| dc.identifier.issn | 0213-3911 | |
| dc.identifier.uri | http://hdl.handle.net/10201/117363 | |
| dc.language | eng | es |
| dc.publisher | Universidad de Murcia. Departamento de Biología Celular e Histología | es |
| dc.relation | Sin financiación externa a la Universidad | es |
| dc.rights | info:eu-repo/semantics/openAccess | es |
| dc.rights | Attribution-NonCommercial-NoDerivatives 4.0 Internacional | * |
| dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | * |
| dc.subject | Myocardial infarction | es |
| dc.subject | Smad | es |
| dc.subject | TGF-β | es |
| dc.subject | BMP | es |
| dc.subject.other | CDU::6 - Ciencias aplicadas::61 - Medicina::616 - Patología. Medicina clínica. Oncología | es |
| dc.title | The expression of Smad signaling pathway in myocardium and potential therapeutic effects | es |
| dc.type | info:eu-repo/semantics/article | es |
| dspace.entity.type | Publication | es |
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