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The controversial nuclear matrix: a balanced point of view

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dc.contributor.authorMartelli, A.M.es
dc.contributor.authorFalcieri, E.es
dc.contributor.authorZweyer, M.
dc.contributor.authorBortul, R.
dc.contributor.authorTabellini, G.
dc.contributor.authorCappellini, A.
dc.contributor.authorCocco, L.
dc.date.accessioned2011-05-11T10:59:10Z
dc.date.available2011-05-11T10:59:10Z
dc.date.issued2002
dc.description.abstractThe nuclear matrix is defined as the residual framework after the removal of the nuclear envelope, chromatin, and soluble components by sequential extractions. According to several investigators the nuclear matrix provides the structural basis for intranuclear order. However, the existence itself and the nature of this structure is still uncertain. Although the techniques used for the visualization of the nuclear matrix have improved over the years, it is still unclear to what extent the isolated nuclear matrix corresponds to an in vivo existing structure. Therefore, considerable scepticism continues to surround the nuclear matrix fraction as an accurate representation of the situation in living cells. Here, we summarize the experimental evidence in favor of, or against, the presence of a diffuse nucleoskeleton as a facilitating organizational nonchromatin structure of the nucleus.es
dc.formatapplication/pdfes
dc.format.extent13es
dc.identifier.issn0213-3911es
dc.identifier.urihttp://hdl.handle.net/10201/20857
dc.languageenges
dc.publisherMurcia : F. Hernándezes
dc.relation.ispartofHistology and histopathologyes
dc.rightsinfo:eu-repo/semantics/openAccesses
dc.subjectNucleuses
dc.subjectSkeletones
dc.subject.otherCDU::6 - Ciencias aplicadas::61 - Medicina::611 - Anatomíaes
dc.titleThe controversial nuclear matrix: a balanced point of viewes
dc.typeinfo:eu-repo/semantics/articlees
dspace.entity.typePublicationes
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Histology and histopathology Vol.17, nº 4 (2002)