Publication:
Structural and functional insights into nucleocytoplasmic transport

Simple item page
dc.contributor.authorBeck, Martines
dc.contributor.authorMedalia, Ohades
dc.date.accessioned2013-01-18T13:36:15Z
dc.date.available2013-01-18T13:36:15Z
dc.date.issued2008
dc.description.abstractThe cell nucleus is surrounded by a double membrane system, the nuclear envelope (NE), with the outer nuclear membrane being continuous with the endoplasmic reticulum. Nuclear pore complexes (NPCs) fuse the inner and outer nuclear membranes, forming aqueous channels that allow free diffusion of small molecules but that also mediate the energy-dependent transport of large macromolecules. The NPC represents the largest known molecular complex and is composed of about 30 different proteins, termed nucleoporins (Nups). Here, we review recent studies that provide novel insight into the structural and functional organization of nucleocytoplasmic transport. In addition, prospects towards a high resolution model of the nuclear pore are discussed.es
dc.formatapplication/pdfes
dc.format.extent9es
dc.identifier.issn0213-3911es
dc.identifier.urihttp://hdl.handle.net/10201/29716
dc.languageenges
dc.publisherMurcia : F. Hernándezes
dc.relation.ispartofHistology and histopathologyes
dc.rightsinfo:eu-repo/semantics/openAccesses
dc.subjectNucleocytoplasmic transportes
dc.subjectNucleoporines
dc.subject.other577 - Bioquímica. Biología molecular. Biofísicaes
dc.titleStructural and functional insights into nucleocytoplasmic transportes
dc.typeinfo:eu-repo/semantics/articlees
dspace.entity.typePublicationes
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
Structural and functional insights into nucleocytoplasmic transport.pdf
Size:
6.1 MB
Format:
Adobe Portable Document Format
Description:
Download
Collections
Histology and histopathology Vol.23, nº8 (2008)