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a-synuclein: between synaptic function and dysfunction

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dc.contributor.authorDi Rosa, G.
dc.contributor.authorPuzzo, D.
dc.contributor.authorSant'Angelo, A.
dc.contributor.authorTrinchese, F.
dc.contributor.authorArancio, O.
dc.date.accessioned2016-12-21T15:21:23Z
dc.date.available2016-12-21T15:21:23Z
dc.date.created2003
dc.date.issued2003
dc.description.abstractAlpha-synuclein belongs to a family of vertebrate proteins, encoded by three different genes: a, ß, and g. The protein has become of interest to the neuroscience community in the last few years after the discovery that a mutation in the a-synuclein gene is associated with familial autosomal-dominant early-onset forms of Parkinson Disease. However, it is not yet clear how the protein is involved in the disease. Several studies have suggested that a-synuclein plays a role in neurotransmitter release and synaptic plasticity. This hypothesis might help elucidate how a-synuclein malfunctioning contributes to the development of a series of disorders known as synucleinopathies.es
dc.formatapplication/pdfes
dc.format.extent9es
dc.identifier.urihttp://hdl.handle.net/10201/51603
dc.languageenges
dc.relation.ispartofseriesVol. 18es
dc.relation.ispartofseriesNº. 4es
dc.rightsinfo:eu-repo/semantics/openAccesses
dc.rightsAn error occurred on the license name.*
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dc.subjectSynucleines
dc.subjectNeurotransmissiones
dc.subject.otherCDU::5 - Ciencias puras y naturales::57 - Biologíaes
dc.titlea-synuclein: between synaptic function and dysfunctiones
dc.typeinfo:eu-repo/semantics/articlees
dspace.entity.typePublicationes
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Histology and histopathology Vol.18, nº 4 (2003)