Publication:
Ultrastructural study of the neuroglial and macrophagic reaction in Wallerian degeneration of the adult rat optic nerve

Simple item page
dc.contributor.authorCarbonell, A.L.es
dc.contributor.authorBoya, J.es
dc.contributor.authorCalvo, J.L.
dc.contributor.authorMarín, J.F.
dc.date.accessioned2011-02-01T08:46:05Z
dc.date.available2011-02-01T08:46:05Z
dc.date.issued1991
dc.description.abstractThe Wallerian degeneration of the optic nerve of adult rat has been studied after destroying the retina. Animals were sacrificed between 4 days and 1 year after the lesion. Different cell types of the optic nerve have been studied ultrastructurally. Our results demonstrate the existence of a population of macrophages, probably of microglial origin, responsible for scavenging degenerated myelin. Astrocytes suffer a process of proliferation and hypertrophy. and are massively stuffed by gliofilaments, leading to a glial scar. These cells apparently do not participate in phagocytic phenomena, while some cytoplasmic inclusions (e.g. lipid droplets) suggest some implication in the local metabolization of some tissue degradation products. Oligodendrocytes do not undergo ultrastructural changes, showing a rather quiescent appearance.es
dc.formatapplication/pdfes
dc.format.extent9es
dc.identifier.issn0213-3911es
dc.identifier.urihttp://hdl.handle.net/10201/18253
dc.languageenges
dc.publisherMurcia : F. Hernándezes
dc.relation.ispartofHistology and histopathologyes
dc.rightsinfo:eu-repo/semantics/openAccesses
dc.subjectOptic nervees
dc.subjectWallerian degenerationes
dc.subject.otherCDU::6 - Ciencias aplicadas::61 - Medicinaes
dc.titleUltrastructural study of the neuroglial and macrophagic reaction in Wallerian degeneration of the adult rat optic nervees
dc.typeinfo:eu-repo/semantics/articlees
dspace.entity.typePublicationes
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
Ultrastructural study of the neuroglial and macrophagic reaction in Wallerian degeneration of the adult rat optic nerve.pdf
Size:
1.15 MB
Format:
Adobe Portable Document Format
Description:
Download
Collections
Histology and histopathology Vol. 6, nº 4 (1991)