Publication: Electron microscopic observations on the formation of elastic fibres in cultures of aortic medial cells and adventitial cells
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Date
1988
Authors
Masumi Akita ; Katsuji Kaneko ; Merker, H. J.
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Publisher
Murcia : F. Hernández
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DOI
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info:eu-repo/semantics/article
Description
Abstract
The formation of elastic fibres was observed
in the cultured cells derived from the tunica media and
the tunica adventitia of mouse aorta.
Bundles of myofilaments with dense bodies were
abundantly observed in the cytoplasm of the cultured
media1 cells, and numerous bundles of microfibrillar
components were present in the intercellular spaces.
Fine granules of approximately 50 nm in diameter were
observed in the bundles of microfibrillar components. lt
was supposed that these fine granules of elastin fused
with each other and formed elastic aggregates and then
formed large elastic clumps.
Numerous bundles of microfibrillar components were
also present in the intercellular spaces of the cultured
adventitial cells. Elastic aggregates were scarcely
observed in the bundles of microfibrillar components.
However, large elastic clumps as observed in the media1
cell culture could not be found in the adventitial cell
culture.
It is suggested that the formation of large elastic
clumps might be related to the sheet structures or
lamellae of elastic fibres in the tunica media.
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