Publication: The contribution of cavernous body biopsy in the diagnosis and treatment of male impotence
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Date
1994
Authors
Malovrouvas, D. ; Petraki, C. ; Constantinidis, E. ; Petraki, K. ; Antoniadis, G. ; Constantinidis, C. ; Kranidis, A.
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Publisher
Murcia : F. Hernández
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DOI
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info:eu-repo/semantics/article
Description
Abstract
This study concerns the results of penile
biopsies in 50 patients aged 27 to 80, with secondary
impotence removed with a biopty gun or during penile
surgery. The biopty gun specimens were equally
representative as the open biopsy ones. The cause and
the degree of erectile dysfunction were determined by
clinical and laboratorial investigation. The histological
study of the cavernous bodies in the patients with
psychogenic impotence revealed normal erectile tissue.
In patients with organic impotence, histological lesions
were graded as mild, moderate or severe. The most
severe lesions were observed in the erectile tissue and in
particular in the smooth muscle of the trabeculae and the
helicine arteries, which had been reduced and replaced
by connective tissue. Histological lesions were found not
only in the arterial but also in the venous leak cases.
There was a correlation between their severity and the
degree of impotence, although of no statistical
significance. The penile biopsy determines the condition
(state) of the functional cavernous smooth muscle tissue,
the integrity of which is essential for the erectile
mechanism as well as for the action of the vasoactive
drugs and the results of vascular surgery. Its important
role is evident as it contributes not only to the diagnosis
of the cause, but also to the choice of treatment of male
impotence.
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