Publication:
Distribution of VIP receptors in the human submandibular gland, an immunohistochemical study

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Distribution of VIP receptors in the human submandibular gland an immunohistochemical study.pdf(3.55 MB)
Date
1998
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Authors
Kusakabe, T. ; Matsuda, H. ; Gono, Y. ; Kawakami, T. ; Kurihara, K. ; Tsukuda, M. ; Takenaka, T.
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Publisher
Murcia : F. Hernández
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DOI
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info:eu-repo/semantics/article
Description
Abstract
Distribution of vasoactive intestinal polypeptide (VIP)-immunoreactive nerve fibers and VIPreceptor (VIP-R)-immunoreactive sites in the human submandibular gland were examined by the peroxidaseantiperoxidase method using the specimens taken from patients that had not received radiotherapy. VIP-immunoreactive fibers were found around both serous and mucous acini, the duct system, and those around the mucous acini were more numerous than those around the serous acini. VIP-R immunoreactivity was restricted to the mucous acini and the intercalated duct segment. The serous acini, striated duct, and excretory ducts lacked VIP-R immunoreactivity. These findings suggest that the mucous acinar cells contain VIP-R, and that VIP-R-mediated VIP action is involved in regulating synthesis of viscous saliva and its release.
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Submandibular gland , Immunohistochemistry
Citation
URI
http://hdl.handle.net/10201/19055
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Histology and histopathology Vol.13, nº 2 (1998)
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