Publication:
Siesta behavior and genetics interact to influence obesity risk

Simple item page
dc.contributor.authorRodriguez-Martín, María
dc.contributor.authorSalmerón Martínez, Diego
dc.contributor.authorDashti, Hassan S.
dc.contributor.authorCascales, Ana Isabel
dc.contributor.authorAragón-Alonso, Aurora
dc.contributor.authorScheer, Frank A. J. L.
dc.contributor.authorSaxena, Richa
dc.contributor.authorGaraulet, Marta
dc.contributor.departmentCiencias Sociosanitarias
dc.date.accessioned2025-01-08T06:56:32Z
dc.date.available2025-01-08T06:56:32Z
dc.date.issued2024-12-23
dc.description© 2024 The Author(s). This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/. This document is the Published version of a Published Work that appeared in final form in Obesity. To access the final edited and published work see https://doi.org/ 10.1002/oby.24173es
dc.description.abstractObjective: In this cross-sectional study, we aim to investigate the interactions between obesity, siesta behavior, and the genetic propensity for siesta in a Mediterranean population, in whom siesta is deeply rooted. Methods: We applied a previously generated Siesta-Polygenic Score (PGS) in the ONTIME study (n = 1278). Siesta and other Mediterranean lifestyle behaviors were characterized using questionnaires. We further determined obesity grade. Secondarily, we measured weight loss during treatment as well as long-term weight-loss mainte nance. Logistic regression analyses were performed to address our aim. Results: A total of 42.4% of the population usually took siesta. A significant genetic influence on siesta propensity was found, with a higher genetic predisposition linked to taking siesta more frequently (odds ratio [OR] = 1.17, 95% CI: 1.03–1.32; p = 0.015). Participants with a higher genetic propensity for siesta showed poorer dietary habits (p < 0.05). Among individuals with a high genetic propensity for siesta, we found that those who usually take siesta have lower odds of having obesity (p =0.038) compared with those who do not. Similarly, in exploratory analysis, among individuals with a high genetic propensity for siesta, we found that those who usually take siesta have higher odds of weight-loss success (p = 0.007) compared with those who do not. Conclusions: Considering the ongoing debate regarding whether siesta is beneficial or detrimental, our findings suggest that individual genetic predisposition to siesta might influence the association between siesta and health.es
dc.formatapplication/pdfes
dc.format.extent13es
dc.identifier.citationObesity (Silver Spring). 2025 33:164–176
dc.identifier.doihttps://doi.org/10.1002/oby.24173
dc.identifier.issnPrint: 1930-7381
dc.identifier.issnElectronic: 1930-739X
dc.identifier.urihttp://hdl.handle.net/10201/147964
dc.languageenges
dc.publisherWileyes
dc.relationThis study was funded by the Spanish Ministry of Science and Innovation (MCINN/AEI) under grant PID2020-112768RB-I00. María Rodríguez-Martín was supported by the MICINN grant PID2020-112768RB-I00. Frank A. J. L. Scheer was supported in part by the National Institutes of Health under grants R01 HL140574 and R01 HL153969.es
dc.relation.publisherversionhttps://onlinelibrary.wiley.com/doi/10.1002/oby.24173
dc.rightsinfo:eu-repo/semantics/openAccesses
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 Internacional*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.titleSiesta behavior and genetics interact to influence obesity riskes
dc.typeinfo:eu-repo/semantics/articlees
dspace.entity.typePublicationes
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
Obesity2024_Siesta_.pdf
Size:
2.9 MB
Format:
Adobe Portable Document Format
Description:
Download
License bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
license.txt
Size:
2.26 KB
Format:
Item-specific license agreed upon to submission
Description:
Download
Collections
Artículos