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Morphometric evidence of the regulation of the activity of LH-immunoreactive cells by corticosterone. An in vivo and in vitro study

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dc.contributor.authorRubio, M.es
dc.contributor.authorCarretero, J.es
dc.contributor.authorCabo, J.J.
dc.contributor.authorSantos, M.
dc.contributor.authorVázquez, R.J.
dc.contributor.authorVázquez, R.
dc.contributor.authorSánchez, F.
dc.date.accessioned2011-02-22T10:33:38Z
dc.date.available2011-02-22T10:33:38Z
dc.date.issued1996
dc.description.abstractThe present study was performed to investigate the morphometric effects of the administration of corticosterone on LH-immunoreactive cells of pituitary monolayer cultures. In addition, the effect of bilateral adrenalectomy on the LH-adenohypophyseal cells was explored. In vitro administration of corticosterone induced a marked decrease in the morphometric parameters considered (cellular, cytoplasmic and nuclear areas). In vivo, bilateral adrenalectomy produced a significant increase in these parameters when compared to those obtained in normal and sham-operated animals. However, when the bilaterally adrenalectomized rats received a daily dose of corticosterone no significant changes in the morphometric parameters were found. Morphometrically, these combined in vivo-in vitro findings confirm a corticosterone-induced hypoactivity of LI4-cells together with a direct effect of this glucocorticoid on LH-adenohypophyseal cells.es
dc.formatapplication/pdfes
dc.format.extent5es
dc.identifier.issn0213-3911es
dc.identifier.urihttp://hdl.handle.net/10201/18895
dc.languageenges
dc.publisherMurcia : F. Hernándezes
dc.relation.ispartofHistology and histopathologyes
dc.rightsinfo:eu-repo/semantics/openAccesses
dc.subjectCorticosteronees
dc.subjectAdrenalectomyes
dc.subject.otherCDU::6 - Ciencias aplicadas::61 - Medicina::611 - Anatomíaes
dc.titleMorphometric evidence of the regulation of the activity of LH-immunoreactive cells by corticosterone. An in vivo and in vitro studyes
dc.typeinfo:eu-repo/semantics/articlees
dspace.entity.typePublicationes
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Histology and histopathology Vol.11, nº 4 (1996)