Publication: Student nurses at Spanish universities and their attitude
toward xenotransplantation
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Date
2019-05
Authors
Martinez Alarcon, Laura ; Rios, Antonio ; Santainés-Borreda, Elena ; Ramirez, Pablo ; Parrilla, Pascual
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Publisher
Wiley
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DOI
https://doi.org/10.1111/xen.12507
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info:eu-repo/semantics/article
Description
© 2019 John Wiley & Sons A/S. .
This document is the published version of a published work that appeared in final form in Xenotransplantation.
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To access the final edited and published work see: https://doi.org/10.1111/xen.12507
Abstract
Abstract
Introduction: Recent immunological and transgenic advances are a promising alternative
using limited materials of human origin for transplantation. However, it is essential
to achieve social acceptance of this therapy.
Objective: To analyze the attitude of nursing students from Spanish universities toward
organ xenotransplantation (XTx) and to determine the factors affecting their
attitude.
Materials and methods: Type of study: A sociological, multicentre, and observational
study. Study population: Nursing students enrolled in Spain (n = 28,000). Sample size:
A sample of 10 566 students estimating a proportion of 76% (99% confidence and
precision of ±1%), stratified by geographical area and year of study. Instrument of
measurement: A validated questionnaire (PCID‐XenoTx‐RIOS) was handed out to
every student in a compulsory session. This survey was self‐administered and selfcompleted
voluntarily and anonymously by each student in a period of 5‐10 min.
Statistical analysis: descriptive analysis, Student's t test, the chi‐square test, and a
logistic regression analysis.
Results: A completion rate: 84% (n = 8913) was obtained. If the results of XTx were as
good as in human donation, 74% (n = 6564) would be in favor and 22% (n = 1946)
would have doubts. The following variables affected this attitude: age (P < 0.001); sex
(P < 0.001); geographical location (P < 0.001); academic year of study (P < 0.001); attitude
toward organ donation (P < 0.001); belief in the possibility of needing a transplant
(P < 0.001); discussion of transplantation with one's family (P < 0.001) and
friends (P < 0.001); and the opinion of one's partner (P < 0.001). The following variables
persisted in the multivariate analysis: being a male (OR = 1.436; P < 0.001); geographical
location (OR = 1.937; P < 0.001); an attitude in favor of donation (OR = 1.519;
P < 0.001); belief in the possibility of needing a transplant (OR = 1.497; P = 0.036);
and having spoken about the issue with family (OR = 1.351; P < 0.001) or friends
(OR = 1.240; P = 0.001).
Conclusions: The attitude of nursing students toward organ XTx is favorable and is
associated with factors of general knowledge about organ donation and transplantation
and social interaction.
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