Publication: A histopathological and morphometrical study of femur
head cartilage in Wistar rats treated with prednisolone
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Date
1989
Authors
Barrueco, J. L. ; Gázquez, A. ; Redondo, E. ; Roncero, V. ; Durán, E.
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DOI
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info:eu-repo/semantics/article
Description
Abstract
An analysis was made of histopathological
developments in femur head cartilage in a group of
Wistar rats receiving a daily intra-muscular injection of
2.5 mg prednisolone. This group was divided into four
experimental batches, each consisting of 6 rats. Batches
were sacrificed at 15,30,60 and 90 days after the start of
the experiment.
Degeneration of the femur head cartilage was observed
from the start of the experiment (15 days), and gave
rise to chondrocyte necrosis by 90 days. Structural
modifications are shown morphologically and morphometrically.
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