Publication: Sulfur dioxide: foe or friend for life?
Authors
Wang, Xin Bao ; Cui, Hong ; Liu, Xiao Hong ; Du, Jun Bao
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Publisher
Universidad de Murcia. Departamento de BiologĂa Celular e HistologĂa
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DOI
DOI: 10.14670/HH-11-904
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info:eu-repo/semantics/article
Description
Abstract
Sulfur dioxide (SO2) is a toxic gas and air
pollutant. The toxic effects of SO2 have been extensively
studied. Oxidative damage due to SO2 can occur in
multiple organs. Inhaled SO2 can also cause
chromosomal aberrations, DNA damage and gene
mutations in mammals. However, SO2 can also be
generated from the sulfur-containing amino acid, Lcysteine. Recent studies have shown that SO2 has a
vasorelaxant effect, and ameliorates pulmonary
hypertension and vascular remodeling. SO2 can also
reduce lung injury and myocardial injury in rats. In
addition, SO2 reduces myocardial ischemia-reperfusion
injury and atherosclerotic lesions. Therefore, SO2 exerts
both detrimental and protective effects in mammals. Is
SO2 a foe or friend for life?
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Citation
Histology and Histopathology, Vol.32, nÂş12, (2017)
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