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Effects of cigarette smoke exposure on the utlrastructure of the golden hamster parathyroid gland

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dc.contributor.authorYano, R.es
dc.contributor.authorHayakawa, D.es
dc.contributor.authorEmura, S.
dc.contributor.authorchen, H.
dc.contributor.authorOzawa, Y.
dc.contributor.authorTaguchi, H.
dc.contributor.authorShoumura, S.
dc.date.accessioned2011-05-11T10:58:04Z
dc.date.available2011-05-11T10:58:04Z
dc.date.issued2002
dc.description.abstractCigarette smoking has been identified as one of the risk factors to induce osteoporosis. However, we find no study on the morphology of the parathy r o i d gland under smoking exposure. We studied the ultrastructure of the parathyroid gland, lung and femur of the golden hamster exposed to cigarette smoke. Fourweek- old male hamsters were housed in a plastic case (48x31x30 cm) and were exposed to cigarette smoke for 12 weeks, 5 minutes exposure, 4 times a day, 4 days a week. There were no differences in serum calcium level and the whole bone mineral density between the control and the smoke-exposed groups. In the parathyroid gland of the smoke - exposed animals, the Golgi complexe s associated with many prosecretory granules were well d eveloped and many secretory granules were located near the plasma membrane. Large lipid-like inclusion bodies were observed in the alveolar macrophages of the smoke-exposed animals. The femur morphology showed a wider area of resorbing surface in the smoke-exposed group than in the control group. From these findings, it is conceivable that the secretory activity of the p a r a t hyroid gland was stimulated with cigarette smoke exposure.es
dc.formatapplication/pdfes
dc.format.extent7es
dc.identifier.issn0213-3911es
dc.identifier.urihttp://hdl.handle.net/10201/20780
dc.languageenges
dc.publisherMurcia : F. Hernándezes
dc.relation.ispartofHistology and histopathologyes
dc.rightsinfo:eu-repo/semantics/openAccesses
dc.subjectParathyroid glandes
dc.subjectSmokinges
dc.subject.otherCDU::6 - Ciencias aplicadas::61 - Medicina::611 - Anatomíaes
dc.titleEffects of cigarette smoke exposure on the utlrastructure of the golden hamster parathyroid glandes
dc.typeinfo:eu-repo/semantics/articlees
dspace.entity.typePublicationes
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Histology and histopathology Vol.17, nº 2 (2002)