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A review of neoplasms with MITF/MiT family translocations

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dc.contributor.authorWei, Shuanzeng
dc.contributor.authorTesta, Joseph R.
dc.contributor.authorArgani, Pedram
dc.date.accessioned2023-02-14T11:12:34Z
dc.date.available2023-02-14T11:12:34Z
dc.date.issued2022
dc.description.abstractMicrophthalmia-associated transcription factor (MITF/MiT) family is a group of basic helix-loophelix leucine zipper (bHLH-LZ) transcription factors including TFE3 (TFEA), TFEB, TFEC and MITF. The first described neoplasms involving MITF family translocation were renal cell carcinomas with chromosome translocations involving ASPLTFE3/t(X;17)(p11.23;q25) or MALAT1-TFEB/t(6;11) (p21.1;q12), and now it is known as MiT family translocation RCC in 2016 WHO classification. Translocations involving MITF family genes also are found in other tumor types, such as perivascular epithelioid cell neoplasm (PEComa), alveolar soft part sarcoma (ASPS), epithelioid hemangioendothelioma, ossifying fibromyxoid tumor (OFMT), and clear cell tumor with melanocytic differentiation and ACTINMITF translocation. In this review, we summarize the features of different types of neoplasms with MITF family translocations.es
dc.formatapplication/pdfes
dc.format.extent11es
dc.identifier.citationHistology and Histopathology Vol. 37, nº4 (2022)
dc.identifier.doihttps://doi.org/10.14670/HH-18-426
dc.identifier.issn0213-3911
dc.identifier.issn1699-5848
dc.identifier.urihttp://hdl.handle.net/10201/128430
dc.languageenges
dc.publisherUniversidad de Murcia, Departamento de Biologia Celular e Histiologiaes
dc.relationSin financiación externa a la Universidades
dc.rightsinfo:eu-repo/semantics/openAccesses
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 Internacional*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subjectMITFes
dc.subjectMiTes
dc.subjectTFE3es
dc.subjectTFEBes
dc.subjectMITFes
dc.subjectTranslocationes
dc.subjectFusion geneses
dc.subjectNeoplasmes
dc.subjectCarcinomaes
dc.subjectSarcomaes
dc.subject.otherCDU::6 - Ciencias aplicadas::61 - Medicina::616 - Patología. Medicina clínica. Oncologíaes
dc.titleA review of neoplasms with MITF/MiT family translocationses
dc.typeinfo:eu-repo/semantics/articlees
dspace.entity.typePublicationes
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Histology and histopathology Vol.37, nº4 (2022)