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Effects of omeprazole on the number of immunoreactive gastrin- and somatostatin-cells in the rat gastric mucosa

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dc.contributor.authorPawlikowski, M.es
dc.contributor.authorKarbownik, M.es
dc.contributor.authorLewinski, A.
dc.contributor.authorPisarek, Hanna
dc.contributor.authorWajs, E.
dc.contributor.authorSzkudlinski, M.
dc.date.accessioned2011-02-01T08:46:43Z
dc.date.available2011-02-01T08:46:43Z
dc.date.issued1992
dc.description.abstractThe effects of omeprazole - an inhibitor of gastric acid secretion - on gastrin (G)- and somatostatin (D)-cell density in the gastric antral mucosa epithelium in rats were examined, following a 5-day treatment. It was found that omeprazole increased the density of G-cells, whereas it decreased the density of D-cells. That effect was probably independent of hypergastrinaemia, since it could not be blocked by a simultaneous treatment with proglumide - a gastrin receptor blocker. It is concluded that the observed phenomenon is a direct result of a lower gastric acidity, as a consequence of omeprazole treatment.es
dc.formatapplication/pdfes
dc.format.extent4es
dc.identifier.issn0213-3911es
dc.identifier.urihttp://hdl.handle.net/10201/18295
dc.languageenges
dc.publisherMurcia : F. Hernándezes
dc.relation.ispartofHistology and histopathologyes
dc.rightsinfo:eu-repo/semantics/openAccesses
dc.subjectGastric antral mucosaes
dc.subjectOmeprazolees
dc.subject.otherCDU::6 - Ciencias aplicadas::61 - Medicinaes
dc.titleEffects of omeprazole on the number of immunoreactive gastrin- and somatostatin-cells in the rat gastric mucosaes
dc.typeinfo:eu-repo/semantics/articlees
dspace.entity.typePublicationes
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Histology and histopathology Vol. 7, nº 2 (1992)