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Morphometric study on the renal glomeruli of streptozotocin (SZ)-induced diabetic APA hamsters

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dc.contributor.authorHan, J.S.es
dc.contributor.authorDoi, K.es
dc.date.accessioned2011-02-01T08:47:39Z
dc.date.available2011-02-01T08:47:39Z
dc.date.issued1992
dc.description.abstractMorphometrical analysis was done on the renal glomeruli of streptozotocin (SZ)-induced diabetic and control APA hamsters. In coincidence with the histopathological and ultrastructural findings, the areas of whole glomerulus (WG) and mesangial region (MR) were significantly larger in diabetic animals than in controls at 1 and 3 months after SZ-injection (1 and 3MAI). The area of capillary lumen in diabetic animals was larger than that in controls at lMAI but it became similar between both groups at 3MAI probably due to an increase in the area of MR. The thickness of basement membrane was significantly larger in diabetic animals than in controls at 3MAI. The present morphometrical findings, together with histological and ultrastructural ones, suggest that SZ-induced diabetic APA hamsters are useful as a model system for the investigation of focal and segmental glomerulosclerosis.es
dc.formatapplication/pdfes
dc.format.extent6es
dc.identifier.issn0213-3911es
dc.identifier.urihttp://hdl.handle.net/10201/18339
dc.languageenges
dc.publisherMurcia : F. Hernándezes
dc.relation.ispartofHistology and histopathologyes
dc.rightsinfo:eu-repo/semantics/openAccesses
dc.subjectMorphometryes
dc.subjectStreptozotocines
dc.subject.otherCDU::6 - Ciencias aplicadas::61 - Medicinaes
dc.titleMorphometric study on the renal glomeruli of streptozotocin (SZ)-induced diabetic APA hamsterses
dc.typeinfo:eu-repo/semantics/articlees
dspace.entity.typePublicationes
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Histology and histopathology Vol. 7, nº 4 (1992)