Biological significance of dietary polyamines

Larqué, Elvira; Zamora, Salvador; Sabater Molina, María

Publication:
Biological significance of dietary polyamines

dc.contributor.author	Larqué, Elvira
dc.contributor.author	Zamora, Salvador
dc.contributor.author	Sabater Molina, María
dc.contributor.department	Ciencias Sociosanitarias
dc.date.accessioned	2024-02-12T11:42:45Z
dc.date.available	2024-02-12T11:42:45Z
dc.date.issued	2006-09-22
dc.description	©2007 Elsevier. This document is the Published, version of a Published Work that appeared in final form in Nutrition. To access the final edited and published work see https://doi.org/10.1016/j.nut.2006.09.006
dc.description.abstract	Polyamines are classically known by their names of putrescine, spermine, and spermidine. They are synthesized endogenously from ornithine and are interconvertible. In addition, an exogenous supply of polyamines is provided by dietary intake and by intestinal absorption from the products of bacterial metabolism. Polyamine uptake occurs almost entirely in the gut, and afterward the various forms are metabolized in different tissues under the strict regulation of ornithine decarboxylase, which is the first enzyme involved in their synthesis. Polyamines are eliminated from the organism by means of oxidation reactions, appearing in urine in all their metabolic forms. Polyamines play an important role in regulating cell growth and proliferation, the stabilization of negative charges of DNA, RNA transcription, protein synthesis, apoptosis, and the regulation of the immune response. They are components of breast milk and might be important in neonatal gut maturation, for which reason the possible supplementation of infant formulas with these compounds is under study.	es
dc.format	application/pdf	es
dc.format.extent	9	es
dc.identifier.citation	Nutrition 23 (2007): 87-95
dc.identifier.doi	https://doi.org/10.1016/j.nut.2006.09.006
dc.identifier.issn	Print: 0899-9007
dc.identifier.uri	http://hdl.handle.net/10201/139281
dc.language	eng	es
dc.publisher	Elsevier
dc.relation	Sin financiación externa a la Universidad	es
dc.rights.accessRights	info:eu-repo/semantics/restrictedAccess
dc.subject	Polyamines
dc.subject	Milk
dc.subject	Gut
dc.subject	Metabolism
dc.subject	Children
dc.title	Biological significance of dietary polyamines	es
dc.type	info:eu-repo/semantics/article	es
dspace.entity.type	Publication	es
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