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An immunocytochemical method for assaying oestrogen receptors in breast cancers. A comparison with the steroid binding assay

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dc.contributor.authorOttestad, Larses
dc.contributor.authorTveit, Kjell M.es
dc.contributor.authorNesland, Jahn M.
dc.contributor.authorDybsjordl, Indrejit
dc.contributor.authorBormer, Ole
dc.contributor.authorHoie, Johan
dc.contributor.authorPihl, Alexander
dc.date.accessioned2011-01-17T12:40:53Z
dc.date.available2011-01-17T12:40:53Z
dc.date.issued1988
dc.description.abstractThe presence of oestrogen receptors was studied in 105 human breast carcinomas using monoclonal antibodies (Abbott ER-ICA kit). The oestrogen receptors of neoplastic cells were semiquantitatively measured and correlations were made to receptor values determined by a dextran-coated charcoal (DCC) steroid binding assay and to histological grade. Immunoreactive cells were found in about 213 of the tumours. Usually only a fraction of the cells within each tumour were immunoreactive, and the staining intensity varied among different cells. In general, well differentiated tumours had a greater proportion of immunoreactive cells than poorly differentiated ones. In most cases (651 98) a good agreement was found between the ER-ICA method and the DCC assay. However, in 33 cases discrepancies were demonstrated.
dc.formatapplication/pdfes
dc.format.extent6es
dc.identifier.issn0213-3911es
dc.identifier.urihttp://hdl.handle.net/10201/17928
dc.languageenges
dc.publisherMurcia : F. Hernándezes
dc.relation.ispartofHistology and histopathologyes
dc.rightsinfo:eu-repo/semantics/openAccesses
dc.subjectBreast carcinomases
dc.subjectImmunocytochemistryes
dc.subject.otherCDU::6 - Ciencias aplicadas::61 - Medicina::616 - Patología. Medicina clínica. Oncologíaes
dc.titleAn immunocytochemical method for assaying oestrogen receptors in breast cancers. A comparison with the steroid binding assayes
dc.typeinfo:eu-repo/semantics/articlees
dspace.entity.typePublicationes
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Histology and histopathology Vol. 3, nº 3 (1988)