Publication:
TGF-B1 and VEGF after fresh frozen bone allograft insertion in oral-maxillo-facial surgery

Simple item page
dc.contributor.authorRodella, L.F.es
dc.contributor.authorFavero, G.es
dc.contributor.authorBoninsegna, R.
dc.contributor.authorBorgonovo, A.
dc.contributor.authorRezzani, R.
dc.contributor.authorSantoro, F.
dc.date.accessioned2015-01-20T12:07:40Z
dc.date.available2015-01-20T12:07:40Z
dc.date.issued2010
dc.description.abstractBone regeneration technique using allografts is widely used in oral surgery to repair alveolar defects and to increase alveolar volume for endosseous implant insertions. Bone allografts promote the reabsorption and neo-synthesis of bone tissue, which are regulated by numerous cytokines, proteins and growth factors. In this study, six patients with insufficient alveolar volume for endosseous implant insertions, were treated with bone regeneration technique using Fresh Frozen Bone (FFB) allografts collected from the femoral head or the hip. Samples of bone graft collected during graft insertion surgery and biopsies collected six months later during implantology were fixed, decalcified and analyzed histomorphologically and morphometrically by haematoxylin-eosin staining. In addition, TGF-ß1 and VEGF were analyzed by immunohistochemistry. The histological analysis of FFBs showed wide areas of calcified bone organized in osteons intermingled with areas of non-calcified matrix containing osteoblasts. However, the regenerated alveolar bone, collected six months after the graft insertion surgery, showed wide areas of non-calcified matrix. TGF-ß1 and VEGF were less expressed in FFB than in regenerated alveolar boneen_EN
dc.formatapplication/pdfes
dc.format.extent9es
dc.identifier.issn0213-3911es
dc.identifier.urihttp://hdl.handle.net/10201/42612
dc.languageenges
dc.publisherMurcia : F. Hernándezes
dc.relation.ispartofHistology and histopathologyes
dc.rightsinfo:eu-repo/semantics/openAccesses
dc.subjectBone regenerationes
dc.subjectTGF-ß1es
dc.subject.other617 - Cirugía. Ortopedia. Oftalmologíaes
dc.titleTGF-B1 and VEGF after fresh frozen bone allograft insertion in oral-maxillo-facial surgeryes
dc.typeinfo:eu-repo/semantics/articlees
dspace.entity.typePublicationes
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
TGFB1 and VEGF after fresh frozen bone allograft insertion in oralmaxillofacial surgery.pdf
Size:
2.3 MB
Format:
Adobe Portable Document Format
Description:
Download
Collections
Histology and histopathology Vol.25, nº4 (2010)