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In vitro differentiation of primordial germ cells and oocyte-like cells from stem cells

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dc.contributor.authorCosta, José J.N.
dc.contributor.authorSouza, Glaucinete B.
dc.contributor.authorSoares, Maria A.A.
dc.contributor.authorRibeiro, Regislane P.
dc.contributor.authorvan den Hurk, Robert
dc.contributor.authorSilva, José R.V.
dc.date.accessioned2022-03-28T08:32:34Z
dc.date.available2022-03-28T08:32:34Z
dc.date.issued2018
dc.description.abstractInfertility is the result of failure due to an organic disorder of the reproductive organs, especially their gametes. Recently, much progress has been made on generating germ cells, including oocytes, from various types of stem cells. This review focuses on advances in female germ cell differentiation from different kinds of stem cells, with emphasis on embryonic stem cells, adult stem cells, and induced pluripotent stem cells. The advantages and disadvantages of the derivation of female germ cells from several types of stem cells are also highlighted, as well as the ability of stem cells to generate mature and functional female gametes. This review shows that stem cell therapies have opened new frontiers in medicine, especially in the reproductive area, with the possibility of regenerating fertility.es
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dc.format.extent12es
dc.identifier.citationHistology and Histopathology, Vol.33, nº2, (2018)
dc.identifier.doiDOI: 10.14670/HH-11-917
dc.identifier.issn1699-5848
dc.identifier.issn0213-3911
dc.identifier.urihttp://hdl.handle.net/10201/118403
dc.languageenges
dc.publisherUniversidad de Murcia. Departamento de Biología Celular e Histologíaes
dc.relationSin financiación externa a la Universidades
dc.rightsinfo:eu-repo/semantics/openAccesses
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 Internacional*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subjectAdult stem cellses
dc.subjectEmbryonic stem cellses
dc.subjectInduced pluripotent stem cellses
dc.subjectPrimordial germ cellses
dc.subjectOocyte-like cellses
dc.subject.otherCDU::6 - Ciencias aplicadas::61 - Medicina::616 - Patología. Medicina clínica. Oncologíaes
dc.titleIn vitro differentiation of primordial germ cells and oocyte-like cells from stem cellses
dc.typeinfo:eu-repo/semantics/articlees
dspace.entity.typePublicationes
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Histology and histopathology Vol.33, nº2 (2018)