Publication: The lectin binding pattern of normal and pathologically altered synovial tissue
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Date
1988
Authors
Zschabitz, A. ; Stofft, E.
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Publisher
Murcia : F. Hernández
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DOI
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info:eu-repo/semantics/article
Description
Abstract
Light-microscopical lectin-binding studies
were carried out in healthy and pathologically altered
synovial tissue (osteoarthrosis, rheumatoid arthritis
(RA)). Seven lectins were studied: Con A, DBA, PNA,
RCA, SBA, UEA-1, and WGA. Con A and WGA mark
al1 lining cells and the majority of subintimal synovial
cells. RCA and SBA stain only a portion of lining cells,
regardless of the basic pathology. The lectin PNA reacts
only with RA and arthrotic material, and is thus suitable
for the diagnosis of inflammatory changes in synovial
tissue. UEA-1 is a consistent marker for capillary
endothelium and large vessels.
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