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In vitro and in vivo characterization of neural stem cells

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dc.contributor.authorBazán, E.es
dc.contributor.authorAlonso, F.J.M.es
dc.contributor.authorRedondo, C.
dc.contributor.authorLópez-Toledano, M.A.
dc.contributor.authorAlfaro, J.M.
dc.contributor.authorReimers, D.
dc.contributor.authorHerranz, A. S.
dc.contributor.authorPaíno, C.L.
dc.contributor.authorSerrano, A.B.
dc.contributor.authorCobacho, N.
dc.contributor.authorCaso, E.
dc.contributor.authorLobo, M.V.T.
dc.date.accessioned2011-06-08T09:09:27Z
dc.date.available2011-06-08T09:09:27Z
dc.date.issued2004
dc.description.abstractNeural stem cells are defined as clonogenic cells with self-renewal capacity and the ability to generate all neural lineages (multipotentiality). Cells with these characteristics have been isolated from the embryonic and adult central nervous system. Under specific conditions, these cells can differentiate into neurons, glia, and non-neural cell types, or proliferate in long-term cultures as cell clusters termed “neurospheres”. These cultures represent a useful model for neurodevelopmental studies and a potential cell source for cell replacement therapy. Because no specific markers are available to unequivocally identify neural stem cells, their functional characteristics (self-renewal and multipotentiality) provide the main features for their identification. Here, we review the experimental and ultrastructural studies aimed at identifying the morphological characteristics and the antigenic markers of neural stem cells for their in vitro and in vivo identification.es
dc.formatapplication/pdfes
dc.format.extent15es
dc.identifier.issn0213-3911es
dc.identifier.urihttp://hdl.handle.net/10201/21619
dc.languageenges
dc.publisherMurcia : F. Hernándezes
dc.relation.ispartofHistology and histopathologyes
dc.rightsinfo:eu-repo/semantics/openAccesses
dc.subjectNeural stem cellses
dc.subjectProgenitor cellses
dc.subject.otherCDU::5 - Ciencias puras y naturales::57 - Biología::576 - Biología celular y subcelular. Citologíaes
dc.titleIn vitro and in vivo characterization of neural stem cellses
dc.typeinfo:eu-repo/semantics/articlees
dspace.entity.typePublicationes
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Histology and histopathology Vol.19, nº 4 (2004)