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Preschool asthma symptoms in children born preterm: the relevance of lung function in infancy

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dc.contributor.authorSánchez-Solís de Querol, Manuel
dc.contributor.authorParra Carrillo, María Soledad
dc.contributor.authorMondéjar López, Pedro Enrique
dc.contributor.authorGarcía Marcos, Patricia W.
dc.contributor.authorGarcía-Marcos Álvarez, Luis Vicente
dc.contributor.departmentCirugía, Pediatría y Obstetricia y Ginecología
dc.contributor.otherFacultades de la UMU::Facultad de Medicina
dc.date.accessioned2026-01-27T12:14:11Z
dc.date.available2026-01-27T12:14:11Z
dc.date.copyright© 2020 by the authors
dc.date.issued2020-10-18
dc.description.abstractBackground: The aim of the study is to assess whether lung function of infants born preterm predicts wheezing in pre-school age. Methods: A survey of the core wheezing questionnaire of the International Study on Asthma and Allergy in Children was administered to parents of preterm newborns, to whom lung function tests were performed at a corrected age of six months, and who, at the time of the survey, were between three and nine years of age. Results: Low values of all lung function parameters measured, except FVC, were predictors of wheezing at some time in life, (FEV0.5 OR: 0.62 (95%CI 0.39; 0.995); FEV0.5/FVC OR: 0.73 (0.54; 0.99)) FEF75 OR: 0.60 [0.37; 0.93]; FEF25-75 OR: 0.57 (0.37; 0.89)); and of wheezing in the past year (FEV0.5 OR: 0.36 (0.17; 0.76); FEV0.5/FVC OR: 0.59 (0.38; 0.93); FEF75 OR: 0.38 [0.19; 0.76]; FEF25-75 OR: 0.35 (0.17; 0.70). In addition, FEV0.5/FVC values lower than the lowest limit of normality, were predictive of hospital admissions due to wheezing (OR: 3.07; (1.02; 9.25)). Conclusions: Limited lung function in infancy is predictive of both future wheezing and hospitalization for a wheezing episode.
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dc.identifier.citationSanchez-Solis M, Parra-Carrillo MS, Mondejar-Lopez P, Garcia-Marcos PW, Garcia-Marcos L. Preschool Asthma Symptoms in Children Born Preterm: The Relevance of Lung Function in Infancy. J Clin Med. 2020;9(10):3345
dc.identifier.doihttps://doi.org/10.3390/jcm9103345
dc.identifier.eissn2077-0383
dc.identifier.urihttp://hdl.handle.net/10201/194929
dc.languageeng
dc.publisherMDPI
dc.relationSin financiación externa a la Universidad
dc.relation.publisherversionhttps://www.mdpi.com/2077-0383/9/10/3345
dc.rightsAttribution 4.0 International*
dc.rights.accessRightsinfo:eu-repo/semantics/openAccess
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/*
dc.subjectPre school asthma
dc.subjectPreterm newborn
dc.subjectInfant lung function
dc.subject.odsObjetivo 3: Salud
dc.titlePreschool asthma symptoms in children born preterm: the relevance of lung function in infancy
dc.typeinfo:eu-repo/semantics/article
dc.type.versioninfo:eu-repo/semantics/publishedVersion
dspace.entity.typePublicationes
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relation.isAuthorOfPublicationfdb051d5-3185-4234-88b6-1cd4ce66e0d4
relation.isAuthorOfPublicationb37b759a-7ec5-43f8-8547-b35602f94cdb
relation.isAuthorOfPublication.latestForDiscoverya20da46d-caef-436f-88c1-5ea0f45ce23e
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