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Biological response to porcine xenograft implants: an experimental study in rabbits

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dc.contributor.authorCalvo Guirado, José Luis
dc.contributor.authorGómez Moreno, Gerardo
dc.contributor.authorGuardia, Javier
dc.contributor.authorOrtiz Ruiz, Antonio José
dc.contributor.authorPiatelli, Adriano
dc.contributor.authorBarone, Antonio
dc.contributor.authorMartínez González, José María
dc.contributor.authorMeseguer Olmo, Luis
dc.contributor.authorLópez Marí, Laura
dc.contributor.authorBarona Dorado, Cristina
dc.contributor.departmentDermatología, Estomatología, Radiología y Medicina Física
dc.date.accessioned2024-06-25T06:58:23Z
dc.date.available2024-06-25T06:58:23Z
dc.date.issued2012-04
dc.description© 2012 by Lippincott Williams & Wilkins. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/ This document is the Published version of a Published Work that appeared in final form in Implant Dentistry. To access the final edited and published work see https://doi.org/10.1097/ID.0b013e3182425991
dc.description.abstractPurpose: The aim of this study was to evaluate the effect of a new porcine biomaterial and collagen paste in 20 New Zealand rabbits. Materials and Methods: Forty implants using a porcine xenograft made up of 80% corticocancellous collagenated bone particles of ≤300 μm in size were placed in the proximal metaphyseal area of both tibiae. Four periods of time were formed: 1h, 5, 8, and 15 months. After implantation, an anteroposterior and lateral radiological study was carried out. Samples were sectioned at 5 μm and stained using hematoxylin-eosin, Masson's trichromic, and Gordon-Switt reticulin stains. Results: These results confirmed the biocompatibility of this porcine biomaterial-collagen paste; only a few, occasional macrophages and scattered lymphocytes were observed. No fibrosis was observed between the implants and the bone. Moreover, the material was osteoconductive acting as a “scaffold” for bone cells, and there was a progressive increase in bone growth in and around the implants. Conclusion: This new porcine biomaterial-collagen paste seemed to be biocompatible, bioresorbable, and osteoconductive.es
dc.formatapplication/pdfes
dc.format.extent6es
dc.identifier.citationImplant Dentistry, 2012, Vol. 21 (2), pp. 112-117
dc.identifier.doihttps://doi.org/10.1097/ID.0b013e3182425991
dc.identifier.issnPrint: 1056-6163
dc.identifier.urihttp://hdl.handle.net/10201/142619
dc.languageenges
dc.publisherLippincott Williams & Wilkinses
dc.relationSin financiación externa a la Universidades
dc.relation.publisherversionhttps://journals.lww.com/implantdent/fulltext/2012/04000/biological_response_to_porcine_xenograft_implants_.8.aspx
dc.rightsinfo:eu-repo/semantics/openAccesses
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 Internacional*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subjectBiomateriales
dc.subjectPorcine bonees
dc.subjectXenograftses
dc.subjectHydroxyapatitees
dc.titleBiological response to porcine xenograft implants: an experimental study in rabbitses
dc.typeinfo:eu-repo/semantics/articlees
dspace.entity.typePublicationes
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