Publication: Endogenous sex hormone and estrogen binding
activity in thyroid cancer
| dc.contributor.author | Imai, Yutaka | |
| dc.contributor.author | Yamakawa, Mitsunori | |
| dc.contributor.author | Matsuda, Mikio | |
| dc.contributor.author | Takeshi, Kasajima | |
| dc.date.accessioned | 2011-01-17T12:40:33Z | |
| dc.date.available | 2011-01-17T12:40:33Z | |
| dc.date.issued | 1989 | |
| dc.description.abstract | Summary. The reactions of four anti-sex hormone (Estrone, Estradiol, Estriol and Testosterone) antisera were immunohistochemically examined in 109 cancerous and 80 normal and benign thyroid tissues. Four kinds of sex hormones were detected in the tumour cells of 61 cases (56%) of thyroid cancer and in the follicular epithelial cells of 4 cases (5%) of normal and benign thyroid tissues. Among the thyroid cancers, 54 female (61%) and 7 cases in males (33%) were positive for sex hormones. Furthermore, estrogen binding activity was screened histochemically in 36 thyroid tissues of various types, and detected not only in thyroid cancer (6115 cases), but in normal and benign thyroid tissues (3121 cases) as well. It was concluded that endogenous estradiol was located in thyroid cancers more frequently in females than in males and that there was estrogen binding activity in the cells of not only thyroid cancers, but also normal and benign thyroid tissues. This is the first report of the dernonstration of endogenous sex hormones in thyroid cancer. | es |
| dc.format | application/pdf | es |
| dc.format.extent | 7 | es |
| dc.identifier.issn | 0213-3911 | |
| dc.identifier.uri | http://hdl.handle.net/10201/17908 | |
| dc.language | eng | es |
| dc.publisher | Murcia : F. Hernández | es |
| dc.relation.ispartof | Histology and Histopathology | es |
| dc.rights | info:eu-repo/semantics/openAccess | es |
| dc.subject | Immunohistochemistry | es |
| dc.subject | Endogenous sex hormone | es |
| dc.subject.other | CDU::6 - Ciencias aplicadas::61 - Medicina | es |
| dc.title | Endogenous sex hormone and estrogen binding activity in thyroid cancer | es |
| dc.type | info:eu-repo/semantics/article | es |
| dspace.entity.type | Publication | es |
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