Publication: Overview of joint tissue alterations in femoroacetabular impingement: What we know through laboratory analyses
Authors
Michela Battistelli ; Eleonora Olivotto ; Giorgia Borciani
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Publisher
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Universidad de Murcia, Departamento de Biologia Celular e Histiologia
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DOI
https://doi.org/10.14670/HH-25-019
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info:eu-repo/semantics/article
Description
Abstract
Hip osteoarthritis (HOA) is the most
common hip joint disorder, accounting for
approximately 27.9% of all cases of osteoarthritis (OA),
often leading to total hip replacement (THR).
In the last decades, femoroacetabular impingement
(FAI) has been addressed as a significant etiological
factor in the development of early-onset HOA,
especially in young adults with non-dysplastic hips.
FAI has been found to cause damage to all joint
tissues, cartilage, labrum, and subchondral bone, thus
underlining the importance of an early diagnosis and
intervention to prevent progression to end-stage disease.
This review aims to provide a comprehensive
overview of the biochemical, morphological, and
cellular alterations occurring in hip joint tissues in the
presence of FAI. Understanding the early pathological
changes is of crucial importance as they often precede
radiographic signs of disease and may serve as valuable
biomarkers for early detection and management of FAI
and peri-arthritic conditions to delay or prevent the need
for THR in younger populations.
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