Suárez Cortés, María

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Suárez Cortés, María

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Suárez Cortés, María

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Universidad de Murcia. Departamento de Enfermería

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Open Access
Inherited epigenetic hallmarks of childhood obesity derived from prenatal exposure to obesogens
(MDPI, 2023-03-07) Núñez-Sánchez, María Á.; Jiménez-Méndez, Almudena; Suárez Cortés, María; Martínez-Sánchez, María A.; Sánchez-Solís de Querol, Manuel; Blanco Carnero, José Eliseo; Ruiz Alcaraz, Antonio José; Ramos-Molina, Bruno; Bioquímica y Biología Molecular B e Inmunología; Facultad de Biología
Childhood obesity has reached epidemic levels in developed countries and is becoming a major cause for concern in the developing world. The causes of childhood obesity are complex and multifactorial, involving the interaction between individual genetics and environmental and developmental factors. Among the environmental factors, there is a growing interest in understanding the possible relationship between the so-called environmental obesogens and the development of obesity in children. Exposure to these obesogens such as phthalates, bisphenol A, or parabens, has been identified as a promoter of obesity through different mechanisms such as the alteration of adipocyte development from mesenchymal progenitors, the interference with hormone receptors, and induced inflammation. However, less attention has been paid to the inheritance of epigenetic modifications due to maternal exposure to these compounds during pregnancy. Thus, the aim of this review is to summarize the current knowledge of epigenetic modifications due to maternal exposure to those obesogens during pregnancy as well as their potential implication on long-term obesity development in the offspring and transgenerational inheritance of epiphenotypes.
Open Access
Self-directed learning in nursing students: a quasi-experimental comparison of two simulation methods
(Elsevier, 2025-09-24) Molina Rodríguez, Alonso; Díaz Agea, José Luis; Cheng, Su-Fen; Lopez-Chicheri-García, Isabel; Suárez Cortés, María; Doménech Asensi, Guillermo; Enfermería; Facultad de Enfermería
Background: Nursing is a dynamic profession requiring self-motivated professionals capable of continually updating their knowledge and skills. Self-directed learning (SDL) is essential to meet evolving clinical demands, and simulation provides innovative approaches to promote it Aim: To examinewhether theSelf-Learning Methodology in Simulated Environments (MAES ) enhances SDL skills in nursing students compared with traditional high-fidelity simulation. Methods: A quasi-experimental study was conducted with 109 undergraduate nursing students. The intervention group (n = 49) applied MAES, where students defined objectives, designed scenarios, and identified resources tailored to their needs. The control group (n = 60) participated in a traditional high-fidelity simulation. SDL ability was assessed with the Self-Directed Learning Instrument (SDLI) at baseline and postintervention. Results: Intra-group analysis showed significant improvement in the MAES group (p = 0.014) compared with the traditional group (p = 0.088). However, between-group comparisons revealed no significant differences (p = 0.157). The most improved dimensions were self-control (time and effort management) and interpersonal communication. Conclusions: MAES shows a favorable trend in fostering SDL, suggesting its potential as an effective educational strategy in nursing.
Open Access
Effectiveness of debriefing after a short training on brief tobacco intervention for nursing students: a randomized clinical trial
(Elsevier , 2025-05-13) Ramos Morcillo, Antonio Jesús; Leal Costa, César; Suárez Cortés, María; Molina Rodríguez, Alonso; Ruzafa Martínez, María; Enfermería; Facultad de Enfermería
Aim: To determine the effectiveness of debriefing after the objective assessment of brief tobacco interventions (BTI) training and its changes after 3 and 9 months. Design: Controlled clinical trial with random assignment by blocks. Methods: 145 sec-year students enrolled in a 4-year nursing degree program participated in the study, with 80 in the intervention group and 65 in the control group. Training according to the 5As (Ask, Advise, Assess, Assist and Arrange) and 5Rs (Relevance, Risks, Rewards, Roadblocks and Repetition) model was provided to both the control and experimental groups as a brief tobacco intervention strategy in primary care. Presentation of three clinical scenarios through videotaped objective structured clinical examination (VOSCE) and assessment with the BTI-St© tool. Posterior debriefing with the experimental group. Descriptive statistical analyses, 2-factor repeated measures ANOVA. Each subject was measured 5 times. (ID protocol: NCT06564766). Results: The time*group interaction results demonstrated significant differences with large effect sizes across all three scenarios. In the experimental groups, the most notable differences were observed immediately after the debriefing compared with baseline. Although these differences decreased over time, they remained present at 3 and 9 months in all scenarios relative to the baseline. Conclusions: The inclusion of debriefing in a brief intervention for learning about BTI within the context of primary care of nursing students resulted in a significant increase in their learning and greater durability, at least after nine months.
Open Access
Job satisfaction in midwives working in labour ward: a systematic review with meta-analysis
(Elsevier, 2024-07-19) Pérez Castejón, Marta; Suárez Cortés, María; Jiménez Ruiz, Ismael; Jiménez Barbero, José Antonio; Enfermería; Facultades de la UMU::Facultad de Enfermería
Abstract Problem: There is little documented evidence of job satisfaction in midwives who work in birthing rooms. Background: Job satisfaction in midwives who work in birthing rooms may have changed in recent decades due to the medicalization of maternal health. Aim: To analyse job satisfaction levels among midwives working in birthing rooms. Methods: We searched Web of Science, SCOPUS, MEDLINE, CUIDEN and CINAHL for observational and mixed method studies. The literature search was carried out from September to October 2022. Findings: A total of 13 studies were included in the systematic review. A meta-analysis of the variable "midwives' job satisfaction" was performed on 12 of the studies. Midwives rated their job satisfaction positively: DME, CI (95%) = 1.24 [0.78, 1.69]. Subgroup 1: DME, CI (95%) = 2.41 [2.05, 2.76]); Subgroup 2: DME, CI (95%) = 0.76 [0.65, 0.86]; subgroup 3: DME, CI (95%) = 1.11 [0.95, 1.27]; subgroup 4: DME, CI (95%) = 0.10 [-0.11, 0.31]. Discussion: Although midwives show high levels of satisfaction, the heterogeneity of instruments, lack of specificity and limited number of studies found restrict the outcomes. Conclusion: There are no specific measurement instruments for assessing job satisfaction among midwives working in labour wards, so it is possible that these data do not correspond to reality as they do not take into account specific professional aspects within this field of practice.
Open Access
Dynamics of the epigenome, microbiome, and metabolome in relation to early adiposity in the maternal–infant axis: protocol for a prospective, observational pilot study in the spanish NEMO cohort
(MDPI, 2025-09-23) Suárez Cortés, María; Juan-Pérez, Almudena; Molina Rodríguez, Alonso; Araújo de Castro, Julia; Castaño Molina, María de los Ángeles; Fernández Ruiz, Virginia Esperanza; Jiménez-Méndez, Almudena; Pérez-Munar, Paula Martínez; Rico-Chazarra, Sara; Ramos-Molina, Bruno; Sánchez-Solís de Querol, Manuel; Blanco Carnero, José Eliseo; Ruiz Alcaraz, Antonio José; Núñez-Sánchez, María Ángeles; Bioquímica y Biología Molecular B e Inmunología; Facultad de Biología
Background: Childhood obesity has reached epidemic levels in developed countries and is an emerging concern in developing regions. Children with excess weight are more likely to maintain this condition over time into adulthood and face a higher risk of developing metabolic disorders such as type 2 diabetes, hypertension, metabolic dysfunction-associated liver disease, and dyslipidemia. Early identification of obesity risk is, therefore, a key public health challenge. Methods: This is an observational, prospective, single-center cohort pilot study in 66 mother–infant dyads recruited at the Gynecology and Obstetrics Service of the Virgen de la Arrixaca University Hospital (Murcia, Spain). The primary objective is to identify early-life, non-invasive biomarkers associated with increased adiposity by integrating multi-omics approaches and analyzing maternal–infant interactions. Pregnant women will be enrolled during the third trimester and will undergo a baseline visit at 38 weeks of gestation for clinical and anthropometric assessment. Buccal swabs and fecal samples will be collected at baseline and in the peripartum period for epigenetic (DNA methylation), metagenomic, and metabolomic analyses. Infants will be evaluated at birth and followed at 6 months, 1 year, 2 years, and 3 years. Each visit will include detailed anthropometric measurements, along with collection of buccal swabs and fecal samples for multi-omics profiling. Conclusions: This multidisciplinary study aims to assess how maternal factors influence infant epigenetic and microbial patterns, and their relation to adiposity development. Early identification of such biomarkers may guide personalized prevention strategies and reduce the long-term burden of obesity-related comorbidities.
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Monitoring the sustainability of a breastfeeding guideline during the COVID-19 pandemic: a mixed-methods study
(Wiley, 2025-02-17) Harillo Acevedo, Francisco David; Molina Rodríguez, Alonso; Ramos Morcillo, Antonio Jesús; Suárez Cortés, María; Ruzafa Martínez, María; Enfermería; Facultad de Enfermería
Aim: To analyse the impact of the COVID- 19 pandemic on the sustainability of a breastfeeding (BF) clinical practice guideline (CPG) for women without COVID- 19, throughout the 5 waves of the pandemic. Desing: A mixed- methods design was utilised. Methods: For the quantitative approach, an interrupted time series design was utilised, as well as the analysis of CPG sustaina bility reports as a qualitative approach. The study setting was in a health area in the Spanish health system from April 2019, until October 2021. The sample was composed of 2239 mother–infant dyads. Results: The exclusive- BF rate at hospital discharge obtained values between 90% and 94.8%, without statistically significant changes. A significant increase in the risk of not starting BF in the first feeding was observed (adjusted odds ratio = 9.36; 95% CI: 1.04–84.13), between the pre- pandemic period and the first wave. Skin- to- skin contact (SSC) decreased in the first wave to 82.20%, and the oscillations observed throughout the pandemic were not statistically significant. In general, the qualitative indicators were maintained. A decrease was observed in the spaces used for postpartum care due to the re- assigning to the intensive care unit. Also, the acquisition of materials and equipment decreased. Conclusions: The measures implemented for the sustainability of the BF CPG during the 5 waves of the pandemic were positive. The programmes of implementation of BF guidelines were shown to resist the COVID- 19 pandemic. Impact: Our findings contribute to the understanding and evolution of the main indicators of the sustainability of a BF CPG on COVID- 19 context, providing details on the magnitude of the effect and the process of change. Reporting Method: The Preferred Reporting Items for observational studies (STROBE) checklist was followed. Patient or Public Contribution: No Patient or Public Contribution.
Open Access
Construction and validation of the “labour ward job satisfaction scale for midwives (LWJSS-M)” in Spain
(BioMed Central, 2025-10-14) Pérez Castejón, Marta; Martínez Alarcón, Laura; Leal Costa, César; Suárez Cortés, María; Vera Pérez, José Antonio; Jiménez Ruiz, Ismael; Enfermería
Background Midwives’ job satisfaction is essential to ensuring high quality obstetric care and promoting the well-being of both women and healthcare professionals. However, the medicalised model of childbirth and role conflicts within multidisciplinary teams reduce job satisfaction and increase burnout, leading to high rates of staff turnover. There is therefore a need to develop a comprehensive tool to assess the job satisfaction of midwives working in birthing rooms. Thus, the aim of this study is to develop and validate the following scale: Satisfacción Laboral en Paritorio para Matronas (SLP-M) [Job Satisfaction of Midwives in the Birthing Room]. Methods A two-phase instrumental study was conducted. Firstly, to develop the new instrument a systematic review with meta-analysis and a phenomenological qualitative study were carried out. An expert content validation and the content validity index were conducted. For the validation, psychometric properties of the scale were analysed: item performance, reliability, evidence of validity and its internal structure. Non-probabilistic sampling was used with a minimum of 10 participants per item. They were midwives involved in childbirth areas and were recruited via online. Results A total of 476 complete responses were recorded, with the scale achieving an overall McDonald’s omega of 0,937. Following confirmatory factor analysis, two items with factor loadings below 0.30 were eliminated and the five-dimension model was selected as a good fit, among which are: professional skills in supporting the childbirth process; functional multidisciplinary team; intraprofessional relationships and cooperation; satisfaction with antenatal education and working conditions/determinants of job satisfaction. Conclusion The SLP-M consists of 37 items with good internal consistency, grouped into five dimensions. This approach is designed to ensure the continued viability of the midwifery profession and the quality of care provided.