Moya Villaescusa, María José

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Moya Villaescusa, María José

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Moya Villaescusa, María José

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Universidad de Murcia. Departamento de Dermatología, Estomatología,Radiología y Medicina Física

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Open Access
Influence of the number of microthreads on marginal bone loss: a five-year retrospective clinical study in humans
(MDPI, 2023-03-20) Jornet García, Alfonso Felipe; Sánchez Pérez, Arturo Joaquín; Planes Nicolás, Pablo; Montoya Carralero, José María; Moya Villaescusa, María José; Dermatología, Estomatología, Radiología y Medicina Física
The purpose of the present study was to evaluate the clinical and radiographic outcomes of the number of microthreads on marginal bone over 5 years. Thirty-two implants were placed in 32 patients with partially edentulous maxillae or mandibles. Two implants with the same characteristics were placed: the first one had a 1 mm crest module and 3 microthreads (Q); and the second one had a 3 mm crest module and nine microthreads (S). The prosthesis was inserted 3 months after implant placement. Clinical and radiographic examinations were performed at the one-week, one-month, and three-month follow-up visits and then every six months until a five-year follow-up period was completed. After 5 years of follow-up, five patients withdrew from the study. Complete data were available for 27 implants, with a 100% implant survival rate. No cases of peri-implantitis were diagnosed. The average bone loss was 0.65 mm (C.I. 0.21–1.09) for Q implants and 0.86 mm (C.I. 0.39–1.33) for S implants, with no statistically significant difference. The bone level does not vary between implants with three and nine microthreads or with a 1 mm and 3 mm crest module. No differences in clinical parameters were found.
Open Access
Influence of age and sex on platelet count: implications for optimizing growth factor-rich plasma preparation
(Medicina Oral, 2025-07-22) Sánchez Pérez, Arturo Joaquín; Palma Sánchez, Ana; Jornet García, Alfonso Felipe; Moya Villaescusa, María José; Montoya Carralero, José María; Dermatología, Estomatología, Radiología y Medicina Física
Background: Growth factor-rich plasma (GFRP) is a biomedical procedure used to promote tissue regeneration. Platelet-rich plasma (PRP) contains higher-than-average platelet concentrations and includes platelet-derived growth factors. As an autologous blood derivative, it is widely used to enhance healing and tissue regeneration . In dentistry, GFRP accelerates soft tissue healing and bone regeneration in procedures such as complex extractions, bone grafts, cyst treatments, and to improve dental implant osseointegration. Objective: To assess the potential influence of age and sex on platelet count, with the aim of optimizing the standardization of therapies involving growth factors. Material and Methods: A cross-sectional, observational, and comparative study was conducted, including a total of 384 patients. Participants were stratified into six groups based on age. From their medical records, the platelet counts obtained from analyses meeting the established inclusion criteria were recorded. Subsequently, the distribution of platelet levels was analyzed according to age groups and sex. Additionally, the potential correlation between platelet count and age was evaluated. Results: The mean platelet count was higher in women (260.9 ± 65.9 x10³/μL) than in men (250.4 ± 62.0 x10³/μL), although the difference was not statistically significant (p = 0.113). A statistically significant negative correlation was found between age and platelet count (r = -0.175; p < 0.01), indicating that platelet count decreases with age, although the correlation coefficient was low. Conclusions: Platelet count varies across the population; therefore, blood extraction for PRP preparation should be adjusted based on age group and sex.
Open Access
An adverse effect of Ocrelizumab treatment in a patient with multiple sclerosis: a case report of necrotizing periodontitis
(Gavin Publishers, 2023-04-04) Montoya Carralero, José María; Sánchez Pérez, Arturo Joaquín; Jornet García, Alfonso Felipe; Moya Villaescusa, María José; Dermatología, Estomatología, Radiología y Medicina Física
Multiple Sclerosis (MS) and Necrotizing Periodontitis (NP) are two diseases whose aetiologies and pathophysiologies do not appear to have a common link; however, treating MS with monoclonal antibodies and the decrease in humoral immunity that this entails can be a trigger or an aggravation in patients who present with quiescent NP. We describe a clinical case of NP, including clinical manifestations, treatment, and evolution during therapy with ocrelizumab and to review risk factors. A rapid progression of NP was evidenced. During the patient’s evolution, she suffered bilateral pneumonia due to coronavirus disease 2019, requiring treatment with corticosteroids and antibiotics, which led to clinical relief of her NP. Based on this case, we believe that regulated dental monitoring of patients with MS before, during, and after the administration of monoclonal antibodies may help prevent periodontal deterioration.
Open Access
Electrical potentiometry with intraoral applications
(MDPI, 2022-07-22) Jornet García, Alfonso Felipe; Sánchez Pérez, Arturo Joaquín; Montoya Carralero, José María; Moya Villaescusa, María José; Dermatología, Estomatología, Radiología y Medicina Física
Dental implants currently in use are mainly made of titanium or titanium alloys. As these metallic elements are immersed in an electrolytic medium, galvanic currents are produced between them or with other metals present in the mouth. These bimetallic currents have three potentially harmful effects on the patient: micro-discharges, corrosion, and finally, the dispersion of metal ions or their oxides, all of which have been extensively demonstrated in vitro. In this original work, a system for measuring the potentials generated in vivo is developed. Specifically, it is an electrogalvanic measurements system coupled with a periodontal probe that allows measurement of the potentials in the peri-implant sulcus. This device was tested and verified in vitro to guarantee its applicability in vivo. As a conclusion, this system is able to detect galvanic currents in vitro and it can be considered capable of being employed in vivo, so to assess the effects they may cause on dental implants.
Open Access
Effect of photofunctionalization with 6 W or 85 W UVC on the degree of wettability of RBM titanium in relation to the irradiation time
(MDPI, 2021-06-11) Sánchez Pérez, Arturo Joaquín; Cano-Millá, Nuria; Moya Villaescusa, María José; Montoya Carralero, José María; Navarro Cuellar, Carlos; Dermatología, Estomatología, Radiología y Medicina Física
Photoactivation with ultraviolet C light can reverse the effects derived from biological ageing by restoring a hydrophilic surface. Ten titanium discs were randomly divided into three groups: a control group, a 6 W group, and an 85 W group. A drop of double-distilled, deionized, and sterile 10 µL water was applied to each of the discs. Each disc was immediately photographed in a standardized and perpendicular manner. Measurements were taken based on the irradiation time (15, 30, 60, and 120 min). UVC irradiation improved the control values in both groups. There was no difference in its effect between the 6 W group and the other groups during the first 30 min. However, after 60 min and up to 120 min, 85 W had a significantly stronger effect. The contact angles with the 85 W ultraviolet light source at 60 and 120 min were 19.43° and 31.41°, respectively, whereas the contact angles for the 6 W UVC source were 73.8° and 61.45°. Power proved to be the most important factor, and the best hydrophilicity result was obtained with a power of 85 W for 60 min at a wavelength of 254 nm.
Open Access
Masticatory efficacy following implant rehabilitation: objective assessment and patient perception through two-color mixing test and Viewgum® software
(MDPI, 2025-06-24) Montoya Carralero, José María; Sánchez Pérez, Arturo Joaquín; Sánchez Olaya, Alba; Jornet García, Alfonso Felipe; Moya Villaescusa, María José; Dermatología, Estomatología, Radiología y Medicina Física
Background: Dental implants enhance masticatory efficiency in edentulous patients, yet discrepancies exist between objective assessments and patient perceptions. This study evaluated masticatory efficiency before and after implant rehabilitation using the two-color mixing test (Hue-Check Gum®) and Viewgum® software Version 1.4. 32-bit, correlating objective data with patient-reported outcomes. Methods: In a prospective study of 30 patients receiving implant-supported prostheses, masticatory efficiency was assessed objectively (VOH values via Viewgum®) and subjectively (10 cm VAS). Statistical analysis included Shapiro–Wilk, paired t-tests (VAS), and Wilcoxon tests (VOH). Correlation and regression analyses examined subjective–objective relationships. Results: Significant improvements occurred post-rehabilitation. VAS scores rose from 3.46 (95% CI: 2.54–4.39) to 7.29 (6.55–8.02; p < 0.001). VOH values decreased from 0.462 (0.426–0.497) to 0.438 (0.403–0.473; p = 0.001), confirming better chewing performance. No correlation was found between VAS and VOH, pre- (p > 0.346) or post-treatment (p > 0.980). Conclusion: Implant rehabilitation improves masticatory function objectively and subjectively. However, the lack of correlation underscores the need for dual assessment in clinical practice. Future studies should explore factors influencing satisfaction and performance to optimize outcomes.
Open Access
Validation of a novel diagnostic test for assessing the risk of Peri-Implantitis through the Identification of the microorganisms present: a pilot clinical study of Periopoc
(MDPI, 2023-08-25) Moya Villaescusa, María José; Sánchez Pérez, Arturo Joaquín; Al-Lal, Nour Mehdi; Jornet García, Alfonso Felipe; Montoya Carralero, José María; Dermatología, Estomatología, Radiología y Medicina Física
The aim of this parallel group study was to determine the clinical applicability of a newly developed bacterial test. We evaluated the ability of the test to detect five bacteria associated with peri-implantitis: Porphyromonas gingivalis, Tannerella forsythia, Aggregatibacter actinomycetemcomitans, Prevotella intermedia, and Treponema denticola. Sensitivity, specificity, and positive and negative predictive values were established. Furthermore, by analyzing the pre-test and post-test probabilities, likelihood ratios were established, and a Fagan nomogram was constructed. As the standard, the clinical criteria of peri-implantitis adopted in the latest classification of peri-implant diseases of 2018 were used. The sample consisted of 13 patients clinically diagnosed with peri-implantitis (various implant brands) with at least 1 year of loading, of whom 11 were included in the study. The healthy group comprised 10 patients who received implants (Ticare inhex hybrid) at the university dental clinic and were monitored and exhibited no signs or symptoms of peri-implantitis during 1 year of loading. The results indicated that this test has high sensitivity and low specificity; therefore, positive results will be of great importance for a confirmatory diagnosis of peri-implantitis. However, the test is not suitable as a screening tool.
Open Access
An objective and subjective evaluation of masticatory efficiency in periodontal patients before and after basic periodontal therapy: a case series study
(MDPI, 2025-04-12) Moya Villaescusa, María José; López Lisón, Claudia; Montoya Carralero, José María; Jornet García, Alfonso Felipe; Sánchez Pérez, Arturo Joaquín; Dermatología, Estomatología, Radiología y Medicina Física
Abstract: Background: Periodontal disease is a multifactorial infectious pathology that affects dental supporting tissues, impacting the health and quality of life of patients. Assessing chewing efficiency before and after periodontal therapy is crucial to better understand its impact on the quality of life of periodontal patients. Thus, the aim of this case series study was to determine whether basic periodontal therapy improves masticatory ability and efficiency in patients with mild to moderate periodontitis. Methods: A prospective, longitudinal, case series study was carried out in 42 periodontal patients treated at the University Odontology Clinic. Masticatory efficiency before and after basic periodontal treatment was assessed using both objective (HueCheck Gum test) and subjective (Quality of Masticatory Function Questionnaire: QMFQ) methods. Results: Significant improvements (p = 0.0001) were observed in periodontal variables such as hygiene index (HI), probing depth (PD), and clinical attachment level (CAL), as well as in the initial and final QMFQ total score (p = 0.045). In addition, significant differences were found in posttreatment QMFQ scores related to parafunctional habits (p = 0.046) and facial patterns, especially in meat consumption (p = 0.042) fruit and vegetable consumption (p = 0.007, p = 0.044). The initial mean HueCheck Gum test values were 0.59 ± 0.09 and the final values were 0.61 ± 0.11. These differences were not statistically significant. Conclusions: Basic periodontal treatment does not objectively improve the masticatory efficiency of patients with mild–moderate periodontitis, evaluated by means of the test of mixing two chewing gums, but it does offer subjective improvements.