Browsing by Subject "Toxic effect"

Now showing 1 - 1 of 1
  • Thumbnail Image
    Publication
    Open Access
    Sulfur dioxide: foe or friend for life?
    (Universidad de Murcia. Departamento de Biología Celular e Histología, 2017) Wang, Xin Bao; Cui, Hong; Liu, Xiao Hong; Du, Jun Bao
    Sulfur dioxide (SO2) is a toxic gas and air pollutant. The toxic effects of SO2 have been extensively studied. Oxidative damage due to SO2 can occur in multiple organs. Inhaled SO2 can also cause chromosomal aberrations, DNA damage and gene mutations in mammals. However, SO2 can also be generated from the sulfur-containing amino acid, Lcysteine. Recent studies have shown that SO2 has a vasorelaxant effect, and ameliorates pulmonary hypertension and vascular remodeling. SO2 can also reduce lung injury and myocardial injury in rats. In addition, SO2 reduces myocardial ischemia-reperfusion injury and atherosclerotic lesions. Therefore, SO2 exerts both detrimental and protective effects in mammals. Is SO2 a foe or friend for life?