Browsing by Subject "Supernumerary teeth"

Now showing 1 - 2 of 2
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    Epiprofin-Sp6. A new player in the regulation of tooth development
    (Murcia : F. Hernández, 2010) Jimenez-Rojo, Lucia; Ibarretxe, Gaskon; Aurrekoetxea, Maitane; de Vega, Susana; Nakamura, Takashi; Yamada, Yoshihiko; Unda, F.
    Odontogenesis is governed by a complex network of intercellular signaling events between the dental epithelium and mesenchyme. This network leads to the progressive determination of tooth shape, and to the differentiation of these tissues into enamel-producing ameloblasts and dentin-producing odontoblasts respectively. Among the main signaling pathways involved in the regulation of tooth development, Bone Morphogenetic Protein (BMP), Sonic hedgehog (Shh) and Wingless-type MMTV integration site (Wnt) pathways have been reported to play significant roles. Recently, the phenotype of mice deficient in Epiprofin/Sp6 (Epfn) has been found to present striking dental abnormalities, including a complete lack of differentiated ameloblasts and consequently no enamel, highly altered molar cusp patterns and the formation of multiple supernumerary teeth. In this article, we review the interaction of Epfn with the BMP, Shh and Wnt pathways in the regulation of tooth development, based on the data obtained from the study of several genetically modified mice.
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    Manejo ortodoncicoquirúrgico de un incisivo central superior impactado debido a un mesiodens
    (Arán Ediciones, 2015) Fernández Miñano, Esther; Hernández Fernández, Ana; Lucas Penalva, P.; Ortiz Ruiz, Antonio José; Dermatología, Estomatología, Radiología y Medicina Física
    Introducción: Los mesiodens son aquellos dientes supernumerarios situados entre distal del 11 y del 21, que representan más del 50% de los supernumerarios. El objetivo es distinguir las señales de alerta de un mesiodens y el momento más adecuado de actuación. Caso clínico: Paciente de 9 años con retraso en la erupción del 21, tras realizar una ortopantomografía se observó la presencia de un mesiodens. Su tratamiento incluyó disyunción, exodoncia del supernumerario y tracción ortodóncica del 21. Discusión: Ante un retraso en la erupción superior a 6 meses, debemos realizar un examen radiológico para descartar la presencia de mesiodens.