Browsing by Subject "Streptococcus pneumoniae"

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    Pneumonia in patients with SARS-CoV-2 infection: series of 17 cases in the region of Murcia
    (Sociedad Española de Quimioterapia, ) Moral Escudero, Encarnación; Hernández Torres, Alicia; Roura Piloto, Aychel Elena; Albendín Iglesias, Helena; Peláez Ballesta, Ana; García Vázquez, Elisa; Medicina
    Introducción. Actualmente la prevalencia de coinfección por neumococo en pacientes con SARS-CoV-2 es desconocida. En este trabajo presentamos sus características clínicas, evolución y tratamiento. Material y métodos. Recogida de datos retrospectivos desde agosto a octubre de 2020 en dos hospitales de la región de Murcia. Resultados. Dieciocho pacientes presentaron COVID-19 diagnosticada por PCR e infección por neumococo confirmada con antigenuria, lo que supuso una prevalencia del 2%. El 88% presentaban alteraciones radiológicas a su ingreso (dos pacientes presentaron una radiografía dentro de la normalidad) y un 29% procalcitonina elevada. La mortalidad de nuestra serie fue del 12%. Conclusiones. Podría ser razonable considerar el inicio de terapia antimicrobiana en aquellos casos en los que se tenga una moderada o alta sospecha de coinfección bacteriana, siendo fundamental la retirada del tratamiento antibiótico de forma precoz si ésta no se confirma.
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    Rapid urinary antigen test for diagnosis of pneumococcal community-acquired pneumonia in adults
    (ERS Journals, 2003) Marcos, M.A.; Jiménez de Anta, M.T.; Bellacasa, J.P. de la; González, J.; Martínez, E.; García-Vázquez, Elisa; Mensa, J.; Roux, A. de; Torres, A.; Medicina
    Streptococcus pneumoniae is suspected to cause an important proportion of community-acquired pneumonia (CAP) whose aetiology cannot be detected withconventional tests. In this study, the authors evaluated the diagnostic yield of a new immunochromatographic membrane test (ICT) for the detection of the S. pneumoniae antigen in the urine of patients admitted with diagnosed CAP. ICT was performed in unconcentrated and concentrated urine from all the patients. ICT was repeated 1 month after discharge in a group initially testing positive. The authors also studied the ICT in clinically stable human immunodeficiency virus type 1 (HIV1)-infected patients. S. pneumoniae antigen was detected in all of the 68 (100%) patients tested with definitive pneumococcal pneumonia. In five of these cases ICT was only positive when it had been performed on the patients. The S. pneumoniae antigen was also detected in 36 (69.2%) of 52 patients with probable pneumococcal pneumonia and in 50 of 277 (18%) patients without pneumococcal pneumonia. ICT remained positive in 16 (69.5%) of 23 patients, 1 month after hospital discharge. Nasopharyngeal colonisation with S. pneumoniae was detected in 8 (12%) of 68 clinically stable HIV1 infected patients, but none tested ICT positive. The Binax NOW1 immunochromatographic membrane test is a rapid, sensitive and specific test for detecting pneumococcal community-acquired pneumonia in adults. The test may remain positive for several weeks after pneumococcal pneumonia.