Browsing by Subject "Nanocapsules"

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    Development and characterization of nanocapsules comprising dodecyltrimethylammonium chloride and K-carrageenan.
    (Elsevier, 2011-03-23) Rosas Durazo, A.; Lizardi, J.; Higuera Ciapara, I.; Argüelles Monal, W.; Goycoolea Valencia, Francisco Martín; Biología Celular e Histología; Facultades de la UMU::Facultad de Biología
    The aim of this work was to develop and characterize a new type of nanocapsules. To this end, a nanoemulsion bearing an oily core (Miglyol 812) was obtained by spontaneous emulsification and stabilized by dodecyl-trimethylammonium chloride (DTAC), a commercial cationic surfactant; this nanoemulsion was coated with proportionally very small amounts of κ-carrageenan (at molar charge ratios of Z ≤ 0.0045) that interact predominantly by an electrostatic mechanism with the positively charged sites at the polar heads of DTAC at the nanoemulsion's surface to harness nanocapsules of average size ∼250–330 nm and zeta potential (ζ) ranging from ∼+80 to +7 mV. The potential application of the new type of developed nanosystems as drug delivery vehicles has yet to be investigated and fully realized.