Browsing by Subject "Large vacuolar body"

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    Effects of prostaglandin Eq on the ultrastructure of the golden hamster parathyroid gland
    (Murcia : F. Hernández, 1994) Emura, S.; Utsumi, M.; Hayakawa, D.; Yamahira, T.; Terasawa, K.; Tamada, A.; Isono, H.; Shoumura, S.
    The effects of different ages on large vacuolar bodies in the parathyroid glands of golden hamsters after administration of prostaglandin E2 (PGE2) were investigated. In the parathyroid glands of the young and senile animals 15 min and the senile animals 60 min after administration of PGE2, the mean serum calcium concentration was significantly higher when compared to that of the young and senile control animals, respectively. In the experimental adult animals 60 min after administration of PGE2, the serum calcium concentration was seen to increase. In the parathyroid glands of the young animals 15 min and the adult and senile animals 60 min after administration of PGE2, the percent area occupied by large vacuolar bodies was significantly increased when compared to that of the young, adult and senile control animals, respectively. These findings suggest that the percent area occupied by large vacuolar bodies is increased in response to hypercalcemia induced by PGE2. It is thought that in the parathyroid glands suppressed by hypercalcemia there is a relationship between the percent area occupied by large vacuolar bodies and aging.
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    Effects of short-term treatment with CaCI2 or EDTA on the parathyroid glands in pregnant golden hamsters, with special reference to large vacuolar bodies
    (Murcia : F. Hernández, 1997) Emura, S.; Hayakawa, D.; chen, H.; Terasawa, K.; Tamada, A.; Isono, H.; Shoumura, S.
    The large vacuolar bodies in the parathyroid glands of pregnant golden hamsters after administration of CaC12 or EDTA were investigated. In the parathyroid glands of the pregnant animals 15 min after administration of CaC12, the mean serum calcium concentration was significantly high when compared to that of the control animals. In the parathyroid glands of the pregnant animals 15, 30 and 60 min after administration of EDTA, the mean serum calcium concentration was significantly low when compared to that of the control animais. In the parathyroid glands of the pregnant animals 15 min after administration of CaC12, the percentage area occupied by large vacuolar bodies was significantly increased when compared to that of the control animals. In the parathyroid glands of the pregnant animals 15 min after administration of EDTA, the percentage area occupied by large vacuolar bodies was significantly decreased when compared to that of the control animals.