Browsing by Subject "Isoproterenol"
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- PublicationOpen AccessEffect of nitrendipine, a calcium antagonist, on cell volumen in rat salivary glands after isoproterenol stimulation(Murcia : F. Hernández, 1991) Carter, Laurie C.; Nickerson, Peter A.Four days of isoproterenol injections induced a marked enlargement of the rat parotid and submandibular glands reflected in significant increases in the absolute and relative wet and dry weight of the glands. The enlargement in parotid gland was attributable at least in part to cellular hypertrophy inasmuch as the average volume per cell of acinar cells increased. In contrast, the average volume of acinar cells in the submandibular gland was decreased as compared to that of control. It is likely that hyperplasia in both groups accounts in part for the enlargement. The slow calcium channel is unlikely involved in the isoproterenolinduced stimulation of the gland, inasmuch as the calcium channel antagonist did not modify the enlargement of the parotid or submandibular glands.
- PublicationOpen AccessEffects of isoproterenol on the fine structure of the hamster parathyroid gland(Murcia : F. Hernández, 1988) Shizuko Shoumura; Yuji Iwasaki; Noriko Ishizaki; Shoichi Emura; Tomo Yamahira; Masaki Ito; Hideo IsonoUltrastructural changes of the parathyroid glands of isoproterenol-treated golden hamsters were investigated. Many chief cells in the parathyroid glands after 5 and 10 minutes of administration of isoproterenol contain well-developed Golgi complexes and granular endoplasmic reticulum, numerous prosecretory granules, and many secretory granules in the peripheral cytoplasm as compared with the control animals. Many chief cells in the parathyroid glands after 1,3,6 and 12 hours of administration have poorly-developed Golgi complexes, granular endoplasmic reticulum, many secretory granules and numerous lipid droplets as compared with the control animals. The morphology of the parathyroid gland after 30 minutes and 24 hours of administration resembles that of the control animals. It is considered that isoproterenol affects the secretory activity of the parathyroid gland.