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Repositorio Institucional de la Universidad de Murcia

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Browsing by Subject "Infantile cortical hyperostosis"

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    Infantile cortical hyperostosis (Caffey disease): ultrastructural and immunohistochemical characterization of the peritrabecular cells
    (Murcia : F. Hernández, 1990) Quacci, Daniela; Pazzaglia, Ugo Ernesto; Dell`Orbo, Carlo; Grazzia Ennas, María
    The ultrastructure and the immunohistochemical pattern of the cells which are responsible for the bone resorption in the cortical infantile hyperostosis were investigated. The osteoclasts present a great positivity to MB1 antigen and a low positivity to OKM5. Mononuclear cells with primary lysosomes, looking like osteoclast ones are present in high concentration in peritrabecular spaces. These cells show a high positivity to OKM5 antigen and a low positivity to MB1 antigen. The mononuclear granulated cells are positive to tartrate-resistent acid phosphatase. The possible common origin and their co-operation in bone resorption is discussed.

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