Browsing by Subject "Characterization"

Now showing 1 - 5 of 5
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    Analysis of the Interactions Between ILP and TLP With Hardware Transactional Memory
    (IEEE Computer Society, 2022-03) Nicolás-Conesa, Víctor; Titos-Gil, Rubén; Fernández-Pascual, Ricardo; Ros, Alberto; Acacio, Manuel E.; Ingeniería y Tecnología de Computadores
    Hardware Transactional Memory (HTM) allows the use of transactions by programmers, making parallel programming easier and theoretically obtaining the performance of fine-grained locks. However, transactions can abort for a variety of reasons, resulting in the squash of speculatively executed instructions and the consequent loss in both performance and energy efficiency. Among the different sources of abort, conflicting concurrent accesses to the same shared memory locations from different transactions are often the prevalent cause. In this work, we characterize, for the first time to the best of our knowledge, how the aggressiveness of the cores in terms of exploiting instruction-level parallelism can interact with thread-level speculation support brought by HTM systems. We observe that altering the size of the structures that support out-of-order and speculative execution changes the number of aborts produced in the execution of transactional workloads on a best-effort HTM implementation. Our results show that a small number of powerful cores is more suitable for high-contention scenarios, whereas under low contention it is preferable to use a larger number of less aggressive cores. In addition, an aggressive core can lead to performance loss in medium-contention scenarios due to an increase in the number of aborts. We conclude that depending on contention, a careful choice over processor aggressiveness can reduce abort ratios.
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    Estrategia procesal y litigación internacional en la Unión Europea: distinción entre materia contractual y extracontractual
    (Universidad Carlos III de Madrid: Área de Derecho Internacional Privado, 2014) Cebrián Salvat, María Asunción; Derecho Financiero, Internacional y Procesal
    Las opciones que tiene un demandante a la hora de interponer su demanda antetribunales de los Estados miembros participantes en el Reglamento Bruselas I pueden variar en función de si dicha acción se considera como materia “contractual” o “delictual o cuasidelictual” a efectos del Reglamento Bruselas I y, en breve, del Reglamento Bruselas I bis. A falta de definición legal, estos conceptos se encuentran en proceso de definición por el TJUE en vía jurisprudencial, lo que puede proporcionar a las partes que planean su estrategia procesal tanto una cierta inseguridad jurídica como una cierta flexibilidad.
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    Liquid biopsy of circulating tumor cells: From isolation, enrichment, and genome sequencing to clinical applications
    (Universidad de Murcia, Departamento de Histología e Histopatología, 2025) Tan Keqin; Zhu Hong; Ma Xuelei; Biología Celular e Histología
    Circulating tumor cells (CTCs), shed from primary tumors into the bloodstream, play a crucial role in metastasis and hold great potential in cancer diagnosis, prognosis, and treatment monitoring. Conventional CTC detection using epithelial biomarkers like epithelial cell adhesion molecule (EpCAM) for immunocapture overlooks mesenchymal-like CTCs with high metastatic potential, spurring the development of non-immunocapture technologies that use biophysical traits for enrichment. Innovations in microfluidic platforms and multi-parametric sorting improve isolation efficiency and address related challenges. Breakthroughs in single-cell genomic and transcriptomic sequencing enable in-depth molecular characterization of CTCs. Clinically, CTC enumeration and molecular profiling are emerging as real-time tools for assessing therapeutic response and predicting outcomes, especially in metastatic breast, prostate, and colorectal cancers. This review focuses on CTC isolation, enrichment techniques, their applications in different tumors, downstream analysis progress, and potential in precision medicine
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    Removal of different dye solutions: A comparison study using a polyamide nf membrane
    (MDPI, 2020-12-10) Hidalgo, A.M.; León, G.; Gómez, M.; Murcia, M.D.; Gómez, E.; Macario, J.A.; Ingeniería Química
    The removal of organic dyes in aquatic media is, nowadays, a very pressing environmental problem. These dyes usually come from industries, such as textiles, food, and pharmaceuticals, among others, and their harm is produced by preventing the penetration of solar radiation in the aquatic medium, which leads to a great reduction in the process of photosynthesis, therefore damaging the aquatic ecosystems. The feasibility of implementing a process of nanofiltration in the purification treatment of an aqueous stream with small size dyes has been studied. Six dyes were chosen: Acid Brown-83, Allura Red, Basic Fuchsin, Crystal Violet, Methyl Orange and Sunset Yellow, with similar molecular volume (from 250 to 380 Å). The nanofiltration membrane NF99 was selected. Five of these molecules with different sizes, shapes and charges were employed in order to study the behavior of the membrane for two system characteristic parameters: permeate flux and rejection coefficient. Furthermore, a microscopy study and a behavior analysis of the membrane were carried out after using the largest molecule. Finally, the Spiegler–Kedem–Katchalsky model was applied to simulate the behavior of the membrane on the elimination of this group of dyes.
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    "They don't have a name for what he is": the strategic de characterization of J. Demme’s Hannibal Lecter
    (Servicio de Publicaciones, Universidad de Murcia, 2019) Cámara Arenas, Enrique
    This essay challenges the myth of Hannibal Lecter, in Demme’s The Silence of the Lambs, as an enigmatic and unclassifiable character. Lecter’s enigma is generated through a largely unexplored process of de-characterization, i.e. by recurrently presenting him through the speech of other characters who describe him as unknowable. After considering Lecter’s case against the background of well-known literary unknowabilities, a deductive phenomenological exploration of Lecter’s de-characterization is carried out with the assistance of tools from the disciplines of personality and social psychology, and supported by empirical evidence from those fields. The demystifying of Lecter’s unreadability does not entail a debasement of the film or the character. On the contrary, Lecter’s de-characterization, albeit a form of narrative manipulation, is viewed as responsible for much of the film’s impact and success. It produces sensitivity-boosting effects; it mediates the indirect characterization of the other characters; and it engages the spectators’ self-image thus contributing importantly to the enjoyment and appreciation of the film.