Browsing by Subject "Chain walking"

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    Ligand-controlled regiodivergent catalytic amidation of unactivated secondary alkyl bromides
    (American Chemical Society, 2021-08-02) Tortajada, Andreu; Menezes Correia, Jose Tiago; Serrano, Eloisa; Monleón, Alicia; Tampieri, Alberto; Day, Craig S.; Juliá Hernández, Francisco; Martin, Ruben; Química Inorgánica
    A regiodivergent Ni-catalyzed amidation of unactivated secondary alkyl bromides is described. The site-selectivity of the amidation event is dictated by subtle differences on the ligand backbone, allowing introduction of the amide function at either the original sp3 carbon−halide bond or at distal sp3 C−H sites within an alkyl side-chain via chain-walking scenarios.