Publication: Immune complex-mediated glomerulopathy in Barbus graellsi infected with Myxobolus Spp
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Date
1993
Authors
Peribañez, M.A. ; Cacho, Emilio del ; Castillo, J.A. ; Arnal, M.C.
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Publisher
Murcia : F. Hernández
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DOI
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info:eu-repo/semantics/article
Description
Abstract
Membranous glomerulonephritis caused in
Barbus graellsi by myxosporidian infections have been
studied by electron microscopy and immunoelectron
microscopy techniques.
This study indicates that Myxosporidian infection
produces a chronic severe aggression. Spores reach the
spleen, the kidney and the liver, where they are trapped
and phagocyted by Melano Macrophage Centres.
Consequently, the commencement of a immunological
response to myxosporidian is evident. Our results show
the presence of immunodeposits in the basement
membrane of the glomeruli, suggesting that they might
initiate glomerulonephritis. The lesion was markedly
similar to immune complex-mediated glomerulonephritis
disease in higher vertebrates.
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