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AgNOR and breast cancer. A study by image analysis

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dc.contributor.authorRonco, A.es
dc.contributor.authorLarran, J.es
dc.contributor.authorLopez, A.
dc.contributor.authorVilches, J.
dc.date.accessioned2011-02-01T09:17:56Z
dc.date.available2011-02-01T09:17:56Z
dc.date.issued1994
dc.description.abstractThe nucleolar organizer regions are used as a new marker in proliferation cell. AgNOR are loops of DNA actively transcribing to ribosomal RNA and they are associated with nonhistone proteins with strong argyrophile. In the present study we correlated the relationships between number and size of AgNOR measured by an automatic image analysis using CAS- 100, in eleven breast carcinomas in different clinical stages and histological grades. We could identify the AgNOR with silver stain; the relationship between the numberlsize and histological gradelclinical stage shows that in normal breast we find one or two AgNOR but this number is larger when the carcinomas are less differentiated. When studied, the size is larger in the normal breast. We can make the same conclusions with the carcinomas which are lymph-node +.es
dc.formatapplication/pdfes
dc.format.extent5es
dc.identifier.issn0213-3911es
dc.identifier.urihttp://hdl.handle.net/10201/18491
dc.languageenges
dc.publisherMurcia : F. Hernándezes
dc.relation.ispartofHistology and histopathologyes
dc.rightsinfo:eu-repo/semantics/openAccesses
dc.subjectBreast canceres
dc.subjectCAS 100es
dc.subject.otherCDU::6 - Ciencias aplicadas::61 - Medicinaes
dc.titleAgNOR and breast cancer. A study by image analysises
dc.typeinfo:eu-repo/semantics/articlees
dspace.entity.typePublicationes
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Histology and histopathology Vol. 9, nº 2 (1994)