Publication:
Rab family small GTPases-mediated regulation of intracellular logistics in neural development

Simple item page
dc.contributor.authorShikanai, Mima
dc.contributor.authorYuzaki, Michisuke
dc.contributor.authorKawauchi, Takeshi
dc.date.accessioned2022-05-11T11:17:01Z
dc.date.available2022-05-11T11:17:01Z
dc.date.issued2018
dc.description.abstractRab family small GTPases play essential roles in various cellular events via the regulation of intracellular logistics comprising a large number of membrane traffic pathways. Emerging evidence reveals the physiological roles of Rab proteins in several tissues, including developing brains. Many Rab proteins, such as Rab5, Rab6, Rab7, Rab8, Rab10, Rab11, Rab17 and Rab18, are shown to regulate neurite outgrowth in PC12 cells and/or axon and dendrite formation in primary cultured neurons. Recent studies have also revealed in vivo roles of several Rab family small GTPases in brain development and its related neurological disorders. In this review, we introduce the physiological function of Rab family proteins in neural development with particular focus on neurite outgrowth and neuronal migration.es
dc.formatapplication/pdfes
dc.format.extent7es
dc.identifier.citationHistology and Histopathology, Vol.33, nÂş8, (2018)
dc.identifier.doiDOI: 10.14670/HH-11-956
dc.identifier.issn1699-5848
dc.identifier.issn0213-3911
dc.identifier.urihttp://hdl.handle.net/10201/119819
dc.languageenges
dc.publisherUniversidad de Murcia. Departamento de BiologĂ­a Celular e HistologĂ­aes
dc.relationSin financiaciĂłn externa a la Universidades
dc.rightsinfo:eu-repo/semantics/openAccesses
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 Internacional*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subjectBrain developmentes
dc.subjectNeurite outgrowthes
dc.subjectNeuronal migrationes
dc.subjectMembrane traffices
dc.subjectEndocytosises
dc.subjectRabes
dc.subjectCdK5es
dc.subjectJNKes
dc.subject.otherCDU::6 - Ciencias aplicadas::61 - Medicina::616 - PatologĂ­a. Medicina clĂ­nica. OncologĂ­aes
dc.titleRab family small GTPases-mediated regulation of intracellular logistics in neural developmentes
dc.typeinfo:eu-repo/semantics/articlees
dspace.entity.typePublicationes
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
Shikanai-33-765-771-2018.pdf
Size:
2.67 MB
Format:
Adobe Portable Document Format
Description:
Download
License bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
license.txt
Size:
1.39 KB
Format:
Item-specific license agreed upon to submission
Description:
Download
Collections
Histology and histopathology Vol.33, nÂş8 (2018)