Publication:
Anaplastic thyroid carcinoma: Updates on WHO classification, clinicopathological features and staging

Thumbnail Image
Files
Abe-36-239-248-2021.pdf(4.09 MB)
Date
2021
relationships.isAuthorOfPublication
relationships.isSecondaryAuthorOf
relationships.isDirectorOf
Authors
Abe, Ichiro ; King-yin Lam, Alfred
item.page.secondaryauthor
item.page.director
Publisher
Universidad de Murcia, Departamento de Biologia Celular e Histiologia
publication.page.editor
publication.page.department
DOI
https://doi.org/10.14670/HH-18-277
item.page.type
info:eu-repo/semantics/article
Description
Abstract
Anaplastic thyroid carcinoma is an uncommon carcinoma representing 1 to 4% of all thyroid cancers. The carcinoma is most common in females of the eight decades. It is a locally advanced cancer with frequent infiltration of surrounding organs, blood vessels and skin of neck. Paraneoplastic manifestations could occur. Approximately half of the patients with anaplastic thyroid carcinoma had distant metastasis with lung and brain as the most frequent sites of metastasis. The median survival of patients with anaplastic thyroid carcinoma reported was from 1 to 6 months. The terminology of the cancer in World Health Organization is "anaplastic thyroid carcinoma" rather than "undifferentiated thyroid carcinoma". In the latest American Joint Committee on Cancer (AJCC) TNM staging system for anaplastic thyroid carcinoma, there are updates on T and N categories. To conclude, updated knowledge of clinicopathological features, classification, pathological staging will improve our understanding of the cancer and will help in the management of the patients with this aggressive cancer.
publication.page.subject
Anaplastic thyroid carcinoma , AJCC , WHO , Staging
Citation
Histology and Histopathology Vol. 36, nº3 (2021)
URI
http://hdl.handle.net/10201/127003
item.page.embargo
Collections
Histology and histopathology Vol.36, nº3 (2021)
Ir a Estadísticas