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Systematic review and meta-analysis of the use of hyaluronic acid injections to restore interproximal papillae

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dc.contributor.authorSánchez Pérez, Arturo Joaquín
dc.contributor.authorVela-García, Tania Rosa
dc.contributor.authorMateos Moreno, Bibiana
dc.contributor.authorJornet García, Alfonso Felipe
dc.contributor.authorNavarro-Cuellar, Carlos
dc.contributor.departmentDermatología, Estomatología, Radiología y Medicina Física
dc.contributor.otherFacultad de Medicina
dc.date.accessioned2026-01-29T11:12:12Z
dc.date.available2026-01-29T11:12:12Z
dc.date.copyright© 2021 by the authors
dc.date.issued2021-11-10
dc.description.abstractThe absence of interdental papillae leads to the appearance of black triangles. For most patients, the appearance of these triangles is an important reason for concern and affects their social relationships. Multiple reconstruction techniques have been developed with different degrees of success and predictability. The main aim of this study was to evaluate the efficiency of hyaluronic acid (HA) injected into interproximal papillae 6 months after injection and to perform a systematic review and meta-analysis. After a systematic review, seven articles were selected: two clinical randomised controlled trials and five clinical trials. In total, 127 patients with a deficiency in upper papillae in the front of the maxilla and jaw were included in the study. The height variable was evaluated (mm) 6 months after HA injection. In total, 166 interproximal papillae were studied. Four articles showed an important difference in favour of intervention. The total result regarding in the injection of HA was favourable with an approximate average filling of 0.47 mm in the height of the interdental papilla. The injection of HA for the reconstruction of deficient papillae in the region of the upper and lower maxilla was a possible option treatment strategy in mild black triangles.
dc.formatapplication/pdf
dc.format.extent9
dc.identifier.citationAppl. Sci. 2021, 11, 10572
dc.identifier.doihttps://doi.org/10.3390/app112210572
dc.identifier.eissn2076-3417
dc.identifier.urihttp://hdl.handle.net/10201/196709
dc.languageeng
dc.publisherMDPI
dc.relationSin financiación externa a la Universidad
dc.relation.publisherversionhttps://www.mdpi.com/2076-3417/11/22/10572
dc.rightsAttribution 4.0 International*
dc.rights.accessRightsinfo:eu-repo/semantics/openAccess
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/*
dc.subjectAesthetics
dc.subjectGingiva
dc.subjectHyaluronic acid
dc.subjectInjections
dc.subjectSurgical procedures
dc.subjectMinimally invasive
dc.subject.odsNo relacionado con ningún objetivo de desarrollo sostenible
dc.titleSystematic review and meta-analysis of the use of hyaluronic acid injections to restore interproximal papillae
dc.typeinfo:eu-repo/semantics/article
dc.type.versioninfo:eu-repo/semantics/publishedVersion
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relation.isAuthorOfPublication386d0c78-cf11-4776-af9b-4c434c553d10
relation.isAuthorOfPublicationeda7ced1-1ebe-47d8-80d5-1e0c1139b6f1
relation.isAuthorOfPublication.latestForDiscovery7ba0b8fd-9530-45d9-aed3-569152fd12de
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