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Bone density around titanium dental implants coating tested/coated with chitosan or melatonin: an evaluation via microtomography in jaws of Beagle dogs

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dc.contributor.authorLópez Valverde, Nansi
dc.contributor.authorLópez Valverde, Antonio
dc.contributor.authorAragoneses, Juan Manuel
dc.contributor.authorMartínez Martínez, Francisco
dc.contributor.authorGonzález Escudero, María C.
dc.contributor.authorRamírez, Juan Manuel
dc.contributor.departmentCirugía, Pediatría y Obstetricia y Ginecología
dc.date.accessioned2025-05-08T11:06:02Z
dc.date.available2025-05-08T11:06:02Z
dc.date.issued2021-06-29
dc.description© 2021 by the authors. This manuscript version is made available under the CC-BY 4.0 license http://creativecommons.org/licenses/by/4.0/ This document is the Published Manuscript version of a Published Work that appeared in final form in Coatings. To access the final edited and published work see https://doi.org/10.3390/coatings11070777
dc.description.abstractPeri-implant bone density plays an important role in the osseointegration of dental implants. The aim of the study was to evaluate via micro-CT, in Hounsfield units, the bone density around dental implants coated with chitosan and melatonin and to compare it with the bone density around implants with a conventional etched surface after 12 weeks of immediate post-extraction placement in the jaws of Beagle dogs. Six dogs were used, and 48 implants were randomly placed: three groups—melatonin, chitosan, and control. Seven 10 mm × 10 mm regions of interest were defined in each implant (2 in the crestal zone, 4 in the medial zone, and 1 in the apical zone). A total of 336 sites were studied with the AMIDE tool, using the Norton and Gamble classification to assess bone density. The effect on bone density of surface coating variables (chitosan, melatonin, and control) at the crestal, medial, and apical sites and the implant positions (P2, P3, P4, and M1) was analyzed at bivariate and multivariate levels (linear regression). Adjusted effects on bone density did not indicate statistical significance for surface coatings (p = 0.653) but did for different levels of ROIs (p < 0.001) and for positions of the implants (p = 0.032). Micro-CT, with appropriate software, proved to be a powerful tool for measuring osseointegration.es
dc.formatapplication/pdfes
dc.format.extent12es
dc.identifier.citationCoatings 2021, 11(7), 777
dc.identifier.doihttps://doi.org/10.3390/coatings11070777
dc.identifier.issnElectronic. 2079-6412
dc.identifier.urihttp://hdl.handle.net/10201/154293
dc.languageenges
dc.publisherMDPI
dc.relationSin financiación externa a la Universidades
dc.relation.publisherversionhttps://www.mdpi.com/2079-6412/11/7/777
dc.rightsinfo:eu-repo/semantics/openAccesses
dc.rightsAtribución 4.0 Internacional*
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/*
dc.subjectTitanium dental implantses
dc.subjectChitosan coatinges
dc.subjectMelatonin coatinges
dc.subjectBone densityes
dc.subjectHounsfield unityes
dc.subjectMicro computed tomographyes
dc.titleBone density around titanium dental implants coating tested/coated with chitosan or melatonin: an evaluation via microtomography in jaws of Beagle dogses
dc.typeinfo:eu-repo/semantics/articlees
dspace.entity.typePublicationes
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