Role of WNT signaling in normal and malignant hematopoiesis

Publication:
Role of WNT signaling in normal and malignant hematopoiesis

dc.contributor.author	Khan, N.I.	es
dc.contributor.author	Bendall, L.	es
dc.date.accessioned	2011-06-30T12:03:02Z
dc.date.available	2011-06-30T12:03:02Z
dc.date.issued	2006
dc.description.abstract	The WNT pathway is a powerful signaling pathway that plays a crucial role in cell fate determination, survival, proliferation and movement in variety of tissues. Abnormalities in the WNT signaling pathway have been implicated in a number of diseases, most notably cancer. Recent exciting evidence suggests that WNT signaling also plays an important role in hematopoietic stem cell self-renewal and progenitor development. In this review we discuss current state of knowledge on WNT signaling in hematopoiesis and extend our focus on aberrant WNT signaling in hematological malignancies.	es
dc.format	application/pdf	es
dc.format.extent	14	es
dc.identifier.issn	0213-3911	es
dc.identifier.uri	http://hdl.handle.net/10201/22671
dc.language	eng	es
dc.publisher	Murcia : F. Hernández	es
dc.relation.ispartof	Histology and histopathology	es
dc.rights	info:eu-repo/semantics/openAccess	es
dc.subject	Hematopoiesis	es
dc.subject	Leukemia	es
dc.subject.other	CDU::6 - Ciencias aplicadas::61 - Medicina::616 - Patología. Medicina clínica. Oncología	es
dc.title	Role of WNT signaling in normal and malignant hematopoiesis	es
dc.type	info:eu-repo/semantics/article	es
dspace.entity.type	Publication	es

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