Sulfoxaflor effects depend on the interaction with other pesticides and Nosema ceranae infection in the honey bee (Apis mellifera)

Urueña, Álvaro; Blasco-Lavilla, Nuria; De la Rúa Tarín, Pilar

Publication:
Sulfoxaflor effects depend on the interaction with other pesticides and Nosema ceranae infection in the honey bee (Apis mellifera)

dc.contributor.author	Urueña, Álvaro
dc.contributor.author	Blasco-Lavilla, Nuria
dc.contributor.author	De la Rúa Tarín, Pilar
dc.contributor.department	Zoología y Antropología Física
dc.date.accessioned	2025-01-20T12:24:32Z
dc.date.available	2025-01-20T12:24:32Z
dc.date.issued	2023-10-01
dc.description	© 2023 The Authors. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/ This document is the Published Manuscript version of a Published Work that appeared in final form in Ecotoxicology and Environmental Safety. To access the final edited and published work see https://doi.org/10.1016/j.ecoenv.2023.115427
dc.description.abstract	Honey bees health is compromised by many factors such as the use of agrochemicals in agriculture and the various diseases that can affect them. Multiple studies have shown that these factors can interact, producing a synergistic effect that can compromise the viability of honey bees. This study analyses the interactions between different pesticides and the microsporidium Nosema ceranae and their effect on immune and detoxification gene expression, sugar consumption and mortality in the Iberian western honey bee (Apis mellifera iberiensis). For this purpose, workers were infected with N. ceranae and subjected to a sugar-water diet with field concentrations of the pesticides sulfoxaflor, azoxystrobin and glyphosate. Increased sugar intake and altered immune and cytochrome P450 gene expression were observed in workers exposed to sulfoxaflor and infected with N. ceranae. None of the pesticides affected Nosema spore production in honey bee gut. Of the three pesticides tested (alone or in combination) only sulfoxaflor increased mortality in honey bees. Taken together, our results suggest that the effects of sulfoxaflor were attenuated in contact with other pesticides, and that Nosema infection leads to increase sugar intake in sulfoxaflor-exposed bees. Overall, this underlines the importance of studying the interaction between different stressors to understand their overall impact not only on honey bee but also on wild bees health.	es
dc.format	application/pdf	es
dc.format.extent	9	es
dc.identifier.citation	Ecotoxicology and Environmental Safety, 2023, Vol. 264 : 115427
dc.identifier.doi	https://doi.org/10.1016/j.ecoenv.2023.115427
dc.identifier.issn	Electronic: 1090-2414
dc.identifier.issn	Print: 0147-6513
dc.identifier.uri	http://hdl.handle.net/10201/148828
dc.language	eng	es
dc.publisher	Elsevier	es
dc.relation	This project received funding from the European Horizon 2020 Research and Innovation Program under Grant agreement no. 773921. N. B-L. was supported by a postdoctoral fellowship (21372/PDGI/20) from the Regional Research Talent and Employability Program cofunded by the S´eneca Foundation (CARM) and the European Social Fund.	es
dc.relation.publisherversion	https://www.sciencedirect.com/science/article/pii/S0147651323009314?via%3Dihub
dc.rights	info:eu-repo/semantics/openAccess	es
dc.rights	Attribution-NonCommercial-NoDerivatives 4.0 Internacional	*
dc.rights.uri	http://creativecommons.org/licenses/by-nc-nd/4.0/	*
dc.subject	Apis mellifera	es
dc.subject	Gene expression	es
dc.subject	Mortality	es
dc.subject	Nosema ceranae	es
dc.subject	Pesticides	es
dc.subject	Sulfoxaflor	es
dc.title	Sulfoxaflor effects depend on the interaction with other pesticides and Nosema ceranae infection in the honey bee (Apis mellifera)	es
dc.type	info:eu-repo/semantics/article	es
dspace.entity.type	Publication	es